Gallardo-Villamil Andrea, Cano-Aguilar Luis E, Pérez-Muñoz Estela, Rojas-Maruri Mauricio, Saez de Ocariz Marimar
Dermatology, National Institute of Pediatrics, Mexico City, MEX.
Dermatology, General Hospital Dr. Manuel Gea González, Mexico City, MEX.
Cureus. 2023 Jul 15;15(7):e41923. doi: 10.7759/cureus.41923. eCollection 2023 Jul.
Pachydermodactyly (PDD) is an uncommon and benign digital fibromatosis of unknown etiology. It is characterized by a fusiform swelling of the medial and lateral sides of the fingers, with unspecific histopathological features of an increased number of fibroblasts, collagen, and mucin deposit in the dermis. Due to its rarity, PDD could be misdiagnosed as rheumatic arthropathies, which could lead to unnecessary immunosuppressant treatments. Here, we report the case of a 16-year-old boy who presented progressive and asymptomatic soft tissue enlargement of multiple fingers in both hands. The histopathological study and X-ray findings correlated with PDD diagnosis. Intralesional corticoid treatment was indicated with a mild improvement.
厚皮性厚骨膜病(PDD)是一种病因不明的罕见良性指纤维瘤病。其特征为手指内外侧呈梭形肿胀,组织病理学表现不具特异性,真皮中成纤维细胞、胶原蛋白和粘蛋白沉积数量增加。由于其罕见性,PDD可能被误诊为风湿性关节病,从而导致不必要的免疫抑制治疗。在此,我们报告一例16岁男孩的病例,该男孩双手多个手指出现进行性且无症状的软组织肿大。组织病理学研究和X线检查结果与PDD诊断相符。采用病灶内注射皮质类固醇治疗,症状有轻度改善。