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单纯软骨修复与同期软骨修复并截骨术治疗膝关节的早期并发症发生率相当。

Early Complication Rates Are Equivalent Between Isolated Cartilage Restoration and Concomitant Cartilage Restoration and Osteotomy of the Knee.

机构信息

Department of Orthopaedic Surgery, University of California-Irvine, Orange, CA, USA.

Department of Orthopaedic Surgery, Sengkang General Hospital, Musculoskeletal Sciences ACP, Singhealth-DukeNUS Graduate Medical School, Sengkang General Hospital, Singapore.

出版信息

Cartilage. 2024 Jun;15(2):94-99. doi: 10.1177/19476035231194769. Epub 2023 Aug 17.

Abstract

OBJECTIVE

Realignment osteotomy performed concomitantly with cartilage restoration typically requires early restricted weightbearing and can add significant morbidity, potentially leading to an increased risk of early perioperative complications. The purpose of this study was to compare the 30-day complication rates after isolated cartilage restoration (ICR) versus concomitant cartilage restoration and osteotomy (CRO) using the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database.

DESIGN

NSQIP registries between 2006 and 2019 were queried using Current Procedural Terminology codes to identify patients undergoing ICR (autologous chondrocyte implantation, osteochondral autograft transfer, or osteochondral allograft transplantation) and CRO (with concomitant high tibial osteotomy, distal femoral osteotomy, and/or tibial tubercle osteotomy). Complications rates between treatment groups were compared using multivariate logistic regression analyses adjusted for sex, age, steroid use, and respiratory status.

RESULTS

A total of 773 ICR and 97 CRO surgical procedures were identified. Mean patient ages were 35.9 years for the ICR group and 31.2 years for the CRO group. Operative time was significantly longer in the CRO group (170.8 min) compared with the ICR group (97.8 min). Multivariate analysis demonstrated no significant differences in rates of PE, VTE, and all-cause readmission between the ICR and CRO groups. No events of wound disruption, SSI and reoperation were found in the CRO group, while the ICR group was characterized by low rates of wound disruption, reoperation, and SSI (<1.1%).

CONCLUSIONS

These findings further support concomitant osteotomy with cartilage restoration when appropriate and aid surgeons in the preoperative counseling of patients undergoing cartilage restoration treatment.

摘要

目的

同时进行的矫正性截骨术和软骨修复通常需要早期限制负重,这会增加显著的发病率,可能导致早期围手术期并发症的风险增加。本研究的目的是使用美国外科医师学会国家手术质量改进计划(ACS-NSQIP)数据库比较单独软骨修复(ICR)与同时进行的软骨修复和截骨术(CRO)的 30 天并发症发生率。

设计

使用当前程序术语代码在 2006 年至 2019 年的 NSQIP 登记处进行查询,以确定接受 ICR(自体软骨细胞植入、骨软骨自体移植物转移或骨软骨同种异体移植)和 CRO(同时进行的高胫骨截骨术、股骨远端截骨术和/或胫骨结节截骨术)的患者。使用多变量逻辑回归分析比较治疗组之间的并发症发生率,并根据性别、年龄、类固醇使用和呼吸状况进行调整。

结果

共确定了 773 例 ICR 和 97 例 CRO 手术。ICR 组的平均患者年龄为 35.9 岁,CRO 组的平均年龄为 31.2 岁。CRO 组的手术时间明显长于 ICR 组(170.8 分钟)。多变量分析显示,ICR 组和 CRO 组的 PE、VTE 和全因再入院率无显著差异。在 CRO 组未发现伤口破裂、SSI 和再次手术的事件,而 ICR 组的伤口破裂、再次手术和 SSI 的发生率较低(<1.1%)。

结论

这些发现进一步支持在适当情况下同时进行截骨术和软骨修复,并帮助外科医生在进行软骨修复治疗前对患者进行术前咨询。

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