Department of Internal Medicine, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, Goyang, Korea.
Korean J Gastroenterol. 2023 Aug 25;82(2):73-83. doi: 10.4166/kjg.2023.079.
Colorectal cancer (CRC), one of the most common cancers worldwide, continues to increase in incidence and mortality rates. This trend is closely linked to changes in dietary habits, which are major risk factors for colorectal cancer. The increase in the incidence of CRC in countries previously considered low-risk and with low socioeconomic status is most likely due to lifestyle and dietary changes. Understanding the influence of dietary factors on the onset of colorectal cancer is essential for prevention and treatment. This review explores the complex interplay between dietary factors and colorectal cancer, focusing on the key nutrients and dietary habits that influence disease onset and progression. The impact of diet on colorectal microbiota and the influence of diet on early-onset colorectal cancer are also reviewed, reviewing recent research on how dietary interventions affect the treatment and recurrence of colorectal cancer. Finally, the future research directions for developing and applying effective dietary intervention strategies are discussed.
结直肠癌(CRC)是全球最常见的癌症之一,其发病率和死亡率持续上升。这种趋势与饮食习惯的变化密切相关,而饮食习惯是结直肠癌的主要危险因素。以前被认为风险较低、社会经济地位较低的国家 CRC 发病率的上升,很可能是由于生活方式和饮食习惯的改变。了解饮食因素对结直肠癌发病的影响对于预防和治疗至关重要。本综述探讨了饮食因素与结直肠癌之间的复杂相互作用,重点关注影响疾病发生和进展的关键营养素和饮食习惯。还回顾了饮食对结直肠微生物群的影响以及饮食对早发性结直肠癌的影响,综述了饮食干预如何影响结直肠癌的治疗和复发的最新研究。最后,讨论了开发和应用有效饮食干预策略的未来研究方向。