Peters Jonathan J P, Mullarkey Tiarnan, Hedley Emma, Müller Karin H, Porter Alexandra, Mostaed Ali, Jones Lewys
Advanced Microscopy Laboratory (AML), Trinity College Dublin, the University of Dublin, Dublin, Ireland.
School of Physics, Trinity College Dublin, the University of Dublin, Dublin, Ireland.
Nat Commun. 2023 Aug 25;14(1):5184. doi: 10.1038/s41467-023-40875-w.
Transmission electron microscopy is a pivotal instrument in materials and biological sciences due to its ability to provide local structural and spectroscopic information on a wide range of materials. However, the electron detectors used in scanning transmission electron microscopy are often unable to provide quantified information, that is the number of electrons impacting the detector, without exhaustive calibration and processing. This results in arbitrary signal values with slow response times that cannot be used for quantification or comparison to simulations. Here we demonstrate and optimise a hardware signal processing approach to augment electron detectors to perform single electron counting.
透射电子显微镜是材料科学和生物科学中的关键仪器,因为它能够提供关于多种材料的局部结构和光谱信息。然而,扫描透射电子显微镜中使用的电子探测器通常无法在未经详尽校准和处理的情况下提供量化信息,即撞击探测器的电子数量。这导致信号值随意且响应时间缓慢,无法用于量化或与模拟结果进行比较。在此,我们展示并优化了一种硬件信号处理方法,以增强电子探测器来执行单电子计数。