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Atl (atlastin) regulates mTor signaling and autophagy in Drosophila muscle through alteration of the lysosomal network.
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Mouse models for hereditary spastic paraplegia uncover a role of PI4K2A in autophagic lysosome reformation.
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Spinster is required for autophagic lysosome reformation and mTOR reactivation following starvation.
Proc Natl Acad Sci U S A. 2011 May 10;108(19):7826-31. doi: 10.1073/pnas.1013800108. Epub 2011 Apr 25.
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Recent progress in autophagic lysosome reformation.
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PSEN2 (presenilin 2) mutants linked to familial Alzheimer disease impair autophagy by altering Ca homeostasis.
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MTOR, PIK3C3, and autophagy: Signaling the beginning from the end.
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Autophagic lysosomal reformation depends on mTOR reactivation in H2O2-induced autophagy.
Int J Biochem Cell Biol. 2016 Jan;70:76-81. doi: 10.1016/j.biocel.2015.11.009. Epub 2015 Nov 14.
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Beneficial effects of rapamycin in a Drosophila model for hereditary spastic paraplegia.
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Molecular mechanism on autophagy associated cardiovascular dysfunction in .
Front Cell Dev Biol. 2025 Mar 3;13:1512341. doi: 10.3389/fcell.2025.1512341. eCollection 2025.
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Loss of Fic causes progressive neurodegeneration in a Drosophila model of hereditary spastic paraplegia.
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Atlastin-1 regulates endosomal tubulation and lysosomal proteolysis in human cortical neurons.
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The Drosophila Nesprin-1 homolog MSP300 is required for muscle autophagy and proteostasis.
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Motor neuron activity enhances the proteomic stress caused by autophagy defects in the target muscle.
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1
The Drosophila melanogaster attP40 docking site and derivatives are insertion mutations of msp-300.
PLoS One. 2022 Dec 14;17(12):e0278598. doi: 10.1371/journal.pone.0278598. eCollection 2022.
2
ER-mitochondria contact sites; a multifaceted factory for Ca signaling and lipid transport.
Front Cell Dev Biol. 2022 Aug 16;10:988014. doi: 10.3389/fcell.2022.988014. eCollection 2022.
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ER as master regulator of membrane trafficking and organelle function.
J Cell Biol. 2022 Oct 3;221(10). doi: 10.1083/jcb.202205135. Epub 2022 Sep 15.
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Lipid Transport from Endoplasmic Reticulum to Autophagic Membranes.
Cold Spring Harb Perspect Biol. 2022 Nov 1;14(11):a041254. doi: 10.1101/cshperspect.a041254.
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In situ architecture of the lipid transport protein VPS13C at ER-lysosome membrane contacts.
Proc Natl Acad Sci U S A. 2022 Jul 19;119(29):e2203769119. doi: 10.1073/pnas.2203769119. Epub 2022 Jul 13.
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Endoplasmic reticulum-mitochondria signaling in neurons and neurodegenerative diseases.
J Cell Sci. 2022 Feb 1;135(3). doi: 10.1242/jcs.248534. Epub 2022 Feb 7.
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ZEISS Airyscan: Optimizing Usage for Fast, Gentle, Super-Resolution Imaging.
Methods Mol Biol. 2021;2304:111-130. doi: 10.1007/978-1-0716-1402-0_5.
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Atlastin 2/3 regulate ER targeting of the ULK1 complex to initiate autophagy.
J Cell Biol. 2021 Jul 5;220(7). doi: 10.1083/jcb.202012091. Epub 2021 May 14.
9
Lysosome biogenesis: Regulation and functions.
J Cell Biol. 2021 Jun 7;220(6). doi: 10.1083/jcb.202102001. Epub 2021 May 5.
10
Mouse models for hereditary spastic paraplegia uncover a role of PI4K2A in autophagic lysosome reformation.
Autophagy. 2021 Nov;17(11):3690-3706. doi: 10.1080/15548627.2021.1891848. Epub 2021 Mar 9.

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