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新冠疫情期间马来西亚药剂师在哮喘管理中的新角色:叙事性综述

Emerging Roles of Malaysian Pharmacists in Asthma Management Amidst the COVID-19 Pandemic: A Narrative Review.

作者信息

Md Khairi Lukman Nul Hakim, Gnanasan Shubashini

机构信息

Department of Clinical Pharmacy, Faculty of Pharmacy, Universiti Teknologi MARA, Selangor, Malaysia.

Department of Pharmacy, Hospital Sultanah Nur Zahirah, Ministry of Health Malaysia, Terengganu, Malaysia.

出版信息

Malays J Med Sci. 2023 Aug;30(4):33-47. doi: 10.21315/mjms2023.30.4.4. Epub 2023 Aug 24.

Abstract

The arrival of COVID-19 pandemic in March 2020 adversely affected every aspect of human life, including the management of asthma. The pandemic has forced clinicians to revisit the application of high-risk aerosol-generating procedures in asthma management, including spirometry and nebuliser therapy. The use of commercial spacers with pressurised metered-dose inhalers to replace nebulisation is limited by the high cost and pandemic-induced stock unavailability of these inhalers. The need for social distancing, healthcare reserves reallocation, and scarce personal protective equipment has promote increased telemedicine uptake for patients' asthma control and monitoring. Malaysian pharmacists have been providing long-term care of asthma through the introduction of the respiratory Medication Therapy Adherence Clinic (MTAC) to empower patients' general health literacy, train and regularly evaluate their inhalation technique, and reinforce the importance of medication compliance. To minimise the use of unplanned healthcare resources and avoidable COVID-19 infection exposure, Malaysian pharmacists need to better support asthma self-management via increased uptake of written Asthma Action Plans (AAPs). Pharmacist-led asthma treatment step-down to attain the lowest effective dose of inhaled corticosteroids (ICS) has become increasingly relevant during the pandemic, as its prolonged use carries risk of numerous side effects and possible hospitalisation. Telepharmacy offers a promising model for exploration and an alternative to the traditional service delivery of asthma education. Despite not being authorised as vaccinators, Malaysian pharmacists hold strong positions in COVID-19 immunisation programmes for pharmacovigilance and advocacy. The pandemic demands an increased role for pharmacists within medication management to prevent patients from the stockpiling that can cause adverse effects on pharmaceutical supply chain. This review intends to summarise the impact of COVID-19 on asthma management, with a focus on the transitional roles of Malaysian pharmacists before and after the pandemic era.

摘要

2020年3月新型冠状病毒肺炎疫情的到来对人类生活的方方面面都产生了不利影响,包括哮喘的管理。这场疫情迫使临床医生重新审视高风险雾化生成程序在哮喘管理中的应用,包括肺功能测定和雾化治疗。使用带有压力定量吸入器的商用储雾罐来替代雾化治疗受到这些吸入器高昂成本以及疫情导致的库存短缺的限制。社交距离的要求、医疗资源储备的重新分配以及个人防护装备的短缺,促使远程医疗在患者哮喘控制和监测方面的应用有所增加。马来西亚药剂师通过引入呼吸药物治疗依从性诊所(MTAC)来提供哮喘的长期护理,以增强患者的总体健康素养,培训并定期评估他们的吸入技术,并强化药物依从性的重要性。为了尽量减少非计划医疗资源的使用并避免可避免的新型冠状病毒肺炎感染暴露,马来西亚药剂师需要通过增加书面哮喘行动计划(AAP)的采用率来更好地支持哮喘自我管理。在疫情期间,由药剂师主导逐步降低哮喘治疗中吸入性糖皮质激素(ICS)的剂量至最低有效剂量变得越来越重要,因为长期使用ICS存在诸多副作用风险以及可能导致住院。远程药房提供了一个有前景的探索模式,是哮喘教育传统服务提供方式的一种替代。尽管未被授权作为疫苗接种者,但马来西亚药剂师在新型冠状病毒肺炎免疫计划中在药物警戒和宣传方面发挥着重要作用。疫情要求药剂师在药物管理中发挥更大作用,以防止患者囤积药物,因为这可能对药品供应链产生不利影响。本综述旨在总结新型冠状病毒肺炎对哮喘管理的影响,重点关注马来西亚药剂师在疫情时代前后的过渡角色。

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