Graduate School, Beijing University of Chinese Medicine, Beijing, China.
Department of Cardiology, Beijing University of Chinese Medicine Shenzhen Hospital (Longgang), Shenzhen, Guangdong, China.
Eur J Med Res. 2023 Sep 1;28(1):311. doi: 10.1186/s40001-023-01220-5.
As the complexity and diversity of the percutaneous coronary intervention (PCI) are being explored and reported, burgeoning research has progressed in this field. However, there is no comprehensive analysis available on PCI-related studies published in the literature. This study aimed to analyze and visualize the changes of scientific output regarding prognosis of coronary heart disease (CHD) after PCI over the past 20 years and to reveal the knowledge domain and development trends in this field by using CiteSpace software.
Relevant articles published over the period 2004-2022 were retrieved from the Web of Science Core Collection database. After manual selection, qualified documents were included and recorded with the information of their title, abstract, keyword, author, descriptor, citation, identifier, publishing year and publishing organization. We transferred the data to CiteSpace V5.8.R2 (Version 5.8.R2) to draw knowledge maps and to conduct co-occurrence analysis, cluster analysis, timeline analysis, burst term detection and citation analysis.
A total of 14,699 literature records were found relating prognosis of CHD after PCI in the past 20 years (2004-2022), including 14,212 original articles and reviews, and they were published in 153 different journals. Publication production has increased annually and a total of 1182 authors, 796 institutes and 147 countries have contributed to these publications. Moreover, the most representative author was Gregg W Stone from the CardioVascular Research Foundation (CVRF) with 368 publications, whose team mainly focused on exploring the efficacy and safety of revascularization and the characteristics of susceptible population. The global productivity ranking was led by the USA with 3326 published papers, followed by Italy (n = 1355), Japan (n = 1080), China (n = 1075) and Germany (n = 937). And the keywords of these publications were "percutaneous coronary intervention" (n = 2271), "outcome" (n = 1756), "mortality" (n = 1730) and "impact" (n = 1334). Other commonly-used words were "predictor" (n = 1324), "intervention" (n = 1310), "angioplasty" (n = 1299), "risk" (n = 1144), "acute myocardial infarction" (n = 1136) and "artery disease" (n = 1098). Cluster analysis showed that 15 high connected clusters were generated with a modularity Q of 0.831 and a weighted mean silhouette of 0.9388 by applying the log-likelihood ratio algorithm, and the top 5 clusters were #0 optical coherence tomography, #1 dual antiplatelet therapy, #2 bleeding, #3 clopidogrel and #4 thrombus aspiration. Furthermore, the frontiers in the field of prognosis of CHD after PCI mainly involved "decision making", "reperfusion", "angioplasty", "balloon", "unstable angina", "dual antiplatelet therapy", "cardiac surgical score", "restenosis", "reperfusion", "thrombolytic therapy", etc. CONCLUSIONS: To sum up, efficacy and safety of different types of stents, the risk factors of restenosis and thrombotic events after PCI, early risk assessment, and secondary prevention and complications of patients with CHD after PCI were research hotspots and frontier topics in the area by bibliometric analysis. The results could provide a comprehensive overview of the research hotspots and frontier topics relating prognosis of CHD after PCI, promoting a better understanding of the knowledge domain and development trends in this field during the past 20 years.
随着经皮冠状动脉介入治疗(PCI)的复杂性和多样性不断被探索和报道,该领域的研究也在蓬勃发展。然而,目前尚无对文献中与 PCI 相关的研究进行全面分析的报道。本研究旨在通过 CiteSpace 软件分析和可视化过去 20 年来 PCI 后冠心病(CHD)预后相关研究的变化,并揭示该领域的知识领域和发展趋势。
从 Web of Science 核心合集数据库中检索 2004-2022 年间发表的相关文章。经过手动选择,合格的文献被纳入并记录其标题、摘要、关键词、作者、描述符、引文、标识符、出版年份和出版机构的信息。我们将数据传输到 CiteSpace V5.8.R2(版本 5.8.R2),以绘制知识图谱并进行共现分析、聚类分析、时间线分析、突发词检测和引文分析。
在过去 20 年(2004-2022 年)中,共发现 14699 篇与 PCI 后 CHD 预后相关的文献记录,包括 14212 篇原始文章和综述,发表在 153 种不同的期刊上。出版物的产量逐年增加,共有 1182 名作者、796 个机构和 147 个国家对这些出版物做出了贡献。此外,最具代表性的作者是来自心血管研究基金会(CVRF)的 Gregg W Stone,他有 368 篇出版物,他的团队主要专注于探索血运重建的疗效和安全性以及易感人群的特征。全球生产力排名以美国为首,发表的论文有 3326 篇,其次是意大利(n=1355)、日本(n=1080)、中国(n=1075)和德国(n=937)。这些出版物的关键词是“经皮冠状动脉介入治疗”(n=2271)、“结果”(n=1756)、“死亡率”(n=1730)和“影响”(n=1334)。其他常用词是“预测因子”(n=1324)、“干预”(n=1310)、“血管成形术”(n=1299)、“风险”(n=1144)、“急性心肌梗死”(n=1136)和“动脉疾病”(n=1098)。聚类分析显示,通过应用对数似然比算法,共生成了 15 个高连接聚类,模块性 Q 为 0.831,加权平均轮廓系数为 0.9388。前 5 个聚类是#0 光学相干断层扫描、#1 双联抗血小板治疗、#2 出血、#3 氯吡格雷和#4 血栓抽吸。此外,PCI 后 CHD 预后领域的前沿主要涉及“决策”、“再灌注”、“血管成形术”、“球囊”、“不稳定型心绞痛”、“双联抗血小板治疗”、“心脏手术评分”、“再狭窄”、“再灌注”、“溶栓治疗”等。
综上所述,通过文献计量分析,不同类型支架的疗效和安全性、PCI 后再狭窄和血栓事件的危险因素、早期风险评估以及 PCI 后 CHD 患者的二级预防和并发症是该领域的研究热点和前沿课题。这些结果可以为 PCI 后 CHD 预后的研究热点和前沿课题提供全面概述,促进对该领域过去 20 年知识领域和发展趋势的更好理解。