Park Seo Young, Kim Hye Jung, Lee Jeeyeon, Jeong Ji Yun, Byun Jungsup, Kim Won Hwa, Park Byunggeon, Hong Jihoon
Department of Radiology, School of Medicine, Kyungpook National University, Kyungpook National University Chilgok Hospital, Daegu, Korea.
Department of Surgery, School of Medicine, Kyungpook National University, Kyungpook National University Chilgok Hospital, Daegu, Korea.
J Breast Cancer. 2023 Aug;26(4):397-402. doi: 10.4048/jbc.2023.26.e36.
Low-grade myofibroblastic sarcoma (LGMFS) is a rare type of sarcoma, and its manifestation as a radiotherapy (RT)-induced sarcoma following RT for breast cancer is even more unusual. To date, only one case of RT-induced mammary myofibroblastic sarcoma (MFS) has been reported. Here we present the case of a 49-year-old woman with LGMFS after undergoing breast-conserving surgery for invasive ductal carcinoma (IDC), and with a history of RT 16 years prior. Due to the rarity of this disease, previous studies have focused primarily on the pathological findings of MFS. In this report however, we present the clinical and radiological features of LGMFS in the retro pectoral area as a rare type of RT-induced sarcoma.
低度恶性肌纤维母细胞肉瘤(LGMFS)是一种罕见的肉瘤类型,其在乳腺癌放疗(RT)后表现为放疗诱发的肉瘤则更为罕见。迄今为止,仅报道过1例放疗诱发的乳腺肌纤维母细胞肉瘤(MFS)。在此,我们报告1例49岁女性,在接受浸润性导管癌(IDC)保乳手术后发生LGMFS,且有16年前放疗史。由于该疾病罕见,既往研究主要集中在MFS的病理表现。然而,在本报告中,我们呈现了胸后区域LGMFS作为一种罕见的放疗诱发肉瘤的临床和放射学特征。