[Preface to the special issue on the 10th anniversary of Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences].

Industrial biotechnology offers great promises to the development of a green, low-carbon and sustainable economy. The Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, which was formally established ten years ago, is an important powerhouse in the field of industrial biotechnology. To date, the Institute has developed a scientific and technological innovation chain, covering from basic research in life sciences to industrial application of biotechnology. On the occasion of the Institute's tenth anniversary, we publish this special issue to review the progress and trends of industrial biotechnology from six aspects, namely expert perspectives, development strategy, cutting-edge research, enabling technology, core technology innovation, and industrialization promotion. This will facilitate the construction of a green and low-carbon circular economy system, and promote the high-quality development of bioeconomy.