加拿大魁北克省 2 只自由放养的黑熊（美洲黑熊）感染甲型 H5N1 流感病毒。
Influenza A(H5N1) Virus Infections in 2 Free-Ranging Black Bears (Ursus americanus), Quebec, Canada.
出版信息
Emerg Infect Dis. 2023 Oct;29(10):2145-2149. doi: 10.3201/eid2910.230548.
Abstract
Wholly Eurasian highly pathogenic avian influenza H5N1 clade 2.3.4.4b virus was isolated from 2 free-ranging black bears with meningoencephalitis in Quebec, Canada. We found that isolates from both animals had the D701N mutation in the polymerase basic 2 gene, previously known to promote adaptation of H5N1 viruses to mammal hosts.
摘要
从加拿大魁北克省 2 只患有脑膜炎的自由放养黑熊中分离出了全欧亚高致病性禽流感 H5N1 谱系 2.3.4.4b 病毒。我们发现，这两只动物的分离株均在聚合酶碱性 2 基因中具有 D701N 突变，该突变先前已知可促进 H5N1 病毒适应哺乳动物宿主。
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