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教育性生活方式干预对重度精神障碍超重/肥胖患者体重及心理健康的影响

The impact of educational lifestyle intervention on body weight and psychological health among overweight/obese patients with severe mental disorders.

作者信息

Zhang Min-Zhe, Shi Jun-Xia, Li Hui, Chen Rui, Zheng Miao-Bing, Yan Li-Jing, Wu Neng-Jian, He Qi-Qiang

机构信息

School of Public Health, Wuhan University, Wuhan, PR China.

Center of Prevention and Control of Pingshan, Shenzhen, PR China.

出版信息

J Affect Disord. 2023 Dec 15;343:71-76. doi: 10.1016/j.jad.2023.09.028. Epub 2023 Sep 21.

Abstract

BACKGROUND

There was a high prevalence of overweight/obesity among patients with severe mental disorders (SMD). However, studies on the lifestyle-based interventions in patients with SMD are limited.

OBJECTIVE

To examine the effects of an educational lifestyle intervention on body weight and psychological health among Chinese community-dwelling overweight/obese patients with SMD.

METHODS

Community-dwelling overweight/obese patients with SMD was recruited from Shenzhen, China in October 2020. They were randomly allocated into intervention group (IG) and control group (CG). Participants in IG received a 12-month educational lifestyle intervention, while the CG was exposed to routine care. A generalized estimating equation model was used to assess the effect of the intervention over time.

RESULTS

A total of 176 subjects (88 in IG and 88 in CG) aged 42.2 ± 10.9 years were included in this study. After adjusting for potential confounders, body weight (p = 0.001), body mass index (BMI, p = 0.001), and waist circumference (p = 0.027) in IG significantly decreased compared with CG after 12 months. Besides, IG had significantly higher life satisfaction than CG after intervention (p = 0.026), whereas significant reductions in depressive symptoms were observed in IG from 26.1 % at baseline to 13.6 % after the intervention (p = 0.027), and the between-group differences were marginally significant (p = 0.086).

CONCLUSION

An educational lifestyle intervention can effectively reduce body weight parameters and improve psychological health in overweight/obese patients with SMD.

摘要

背景

重度精神障碍(SMD)患者中超重/肥胖的患病率很高。然而,关于基于生活方式的干预对SMD患者影响的研究有限。

目的

探讨教育性生活方式干预对中国社区居住的超重/肥胖SMD患者体重和心理健康的影响。

方法

2020年10月从中国深圳招募社区居住的超重/肥胖SMD患者。他们被随机分为干预组(IG)和对照组(CG)。IG组的参与者接受为期12个月的教育性生活方式干预,而CG组接受常规护理。使用广义估计方程模型评估干预随时间的效果。

结果

本研究共纳入176名年龄为42.2±10.9岁的受试者(IG组88名,CG组88名)。在调整潜在混杂因素后,12个月后IG组的体重(p = 0.001)、体重指数(BMI,p = 0.001)和腰围(p = 0.027)与CG组相比显著下降。此外,干预后IG组的生活满意度显著高于CG组(p = 0.026),而IG组的抑郁症状从基线时的26.1%显著降至干预后的13.6%(p = 0.027),组间差异边缘显著(p = 0.086)。

结论

教育性生活方式干预可有效降低超重/肥胖SMD患者的体重参数并改善其心理健康。

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