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世界卫生组织肥大细胞增多症分类和诊断:2023 年更新和未来展望。

World Health Organization Classification and Diagnosis of Mastocytosis: Update 2023 and Future Perspectives.

机构信息

Division of Hematology and Hemostaseology, Department of Internal Medicine I, Ludwig Boltzmann Institute for Hematology and Oncology, Medical University of Vienna, Wäheringer Gürtel 18-20, A-1090 Vienna, Austria.

Institute of Pathology, Paracelsus Medical University Salzburg, Austria.

出版信息

Immunol Allergy Clin North Am. 2023 Nov;43(4):627-649. doi: 10.1016/j.iac.2023.04.011. Epub 2023 Jul 18.

Abstract

Experts of the European Competence Network on Mastocytosis (ECNM) and the American Initiative on Mast Cell Disorders have discussed and updated diagnostic criteria and the classification of mastocytosis, based on new insights in the field and data collected in recent years, mostly within ECNM registry projects in which studies on several thousand cases have been performed. Based on this proposal, the World Health Organization has updated its classification of mastocytosis. This article discusses the revised classification of mastocytosis in light of a rapidly moving field and the advent of new diagnostic parameters, new prognostication tools, and new therapies.

摘要

欧洲肥大细胞增多症专业网络(ECNM)和美国肥大细胞疾病倡议组织的专家们根据该领域的新见解和近年来收集的数据,讨论并更新了肥大细胞增多症的诊断标准和分类,这些数据主要来自 ECNM 登记项目,其中已经对数千例病例进行了研究。基于这一提议,世界卫生组织更新了其肥大细胞增多症的分类。本文根据快速发展的领域和新的诊断参数、新的预后工具以及新的治疗方法,讨论了肥大细胞增多症的修订分类。

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