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颈椎前路椎间盘切除融合术后迟发性脑脊液漏

Delayed cerebrospinal fluid (CSF) leak following anterior cervical discectomy and fusion surgery.

作者信息

Halayqeh Sereen, Glueck Jacob, Balmaceno-Criss Mariah, Alsoof Daniel, McDonald Christopher L, Diebo Bassel G, Daniels Alan H

机构信息

Department of Orthopedic Surgery, Warren Alpert Medical School, Brown University, 1 Kettle Point Ave East Providence, RI, 02914 United States.

Warren Alpert Medical School, Brown University, 222 Richmond St., RI, 02903 United States.

出版信息

N Am Spine Soc J. 2023 Aug 27;16:100271. doi: 10.1016/j.xnsj.2023.100271. eCollection 2023 Dec.

Abstract

BACKGROUND

An uncommon complication of anterior cervical discectomy and fusion (ACDF) is dura tear, which may be further complicated by cerebral spinal fluid (CSF) leak. Dural tears with CSF leak can lead to catastrophic neurologic outcomes and should be recognized early.

CASE DESCRIPTION

This case report describes a 43-year-old female patient with history of Ehlers-Danlos syndrome who presented 1-year post-ACDF with positional headaches and lightheadedness. Imaging revealed ACDF plate subsidence and CSF leak with inferior displacement of the cerebellar tonsils.

OUTCOME

The patient underwent a revision procedure with removal of index screws and CSF repair using epidural blood patch, fat graft, and Tisseel. The original bicortical screws were replaced with shorter larger diameter unicortical screws. Post-operative imaging at 2 and 6 weeks confirmed resolution of CSF leak.

CONCLUSIONS

Healthcare professionals and patients undergoing spinal surgery should be aware of late presentation CSF leaks which can represent gradual decline in neurological function. Surgical candidates at risk to develop CSF leaks should be counseled about possible complications in preoperative planning.

摘要

背景

颈椎前路椎间盘切除融合术(ACDF)的一种罕见并发症是硬脑膜撕裂,这可能会因脑脊液(CSF)漏出而进一步复杂化。伴有脑脊液漏的硬脑膜撕裂可导致灾难性的神经功能后果,应尽早识别。

病例描述

本病例报告描述了一名43岁患有埃勒斯-当洛综合征的女性患者,她在ACDF术后1年出现体位性头痛和头晕。影像学检查显示ACDF钢板下沉以及脑脊液漏,小脑扁桃体向下移位。

结果

患者接受了翻修手术,取出原螺钉,并使用硬膜外血贴、脂肪移植和纤维蛋白胶进行脑脊液修复。原来的双皮质螺钉被换成了直径更大的较短单皮质螺钉。术后2周和6周的影像学检查证实脑脊液漏已消失。

结论

医疗保健专业人员和接受脊柱手术的患者应意识到迟发性脑脊液漏的出现,这可能表现为神经功能的逐渐下降。在术前规划中,应对有发生脑脊液漏风险的手术候选人告知可能的并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e584/10522904/d0cf059219a1/gr1.jpg

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