Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Center for Cognitive and Computational Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Sci Rep. 2023 Sep 30;13(1):16432. doi: 10.1038/s41598-023-42444-z.
Previous research has suggested that classical psychedelics can foster significant and enduring changes in personality traits and subjective wellbeing. Despite the lack of evidence for adverse effects on mental health stemming from psychedelic use, concerns persist regarding the capacity of these substances to modulate information processing and attitudes towards factual data. The aim of the present study was to investigate the propensity for accepting alternative facts and the general treatment of knowledge within a sample of 392 participants, 233 of whom reported at least a single incidence of psychedelic use in their lifetime. To do this, we leveraged step-wise methods of linear modelling investigating effects of demographics, psychiatric conditions and concomitant drug use. Our findings revealed a moderate positive association between psychedelic use and beliefs in alternative facts, as well as the specific belief that facts are politically influenced. However, no links were found for favouring intuition over evidence when confirming facts. Among other investigated drugs, only alcohol was negatively associated with beliefs in alternative facts. Taken together, our results support the link between psychedelic use and non-conformist thinking styles, which can be attributed to the psychological effects of the drugs themselves, but may also mirror a common trait related to unconventional beliefs and illicit substance use.
先前的研究表明,经典迷幻剂可以促进人格特质和主观幸福感的显著和持久变化。尽管没有证据表明迷幻剂的使用会对心理健康产生不良影响,但人们仍然担心这些物质能够调节信息处理和对事实数据的态度。本研究的目的是在 392 名参与者的样本中调查接受替代事实的倾向和一般知识处理,其中 233 名参与者报告在他们的一生中至少有一次使用迷幻剂的经历。为此,我们利用逐步线性模型方法调查了人口统计学、精神疾病状况和伴随药物使用的影响。我们的研究结果表明,迷幻剂的使用与对替代事实的信念以及事实受到政治影响的具体信念之间存在中度正相关。然而,在确认事实时,对于用直觉代替证据的偏好,没有发现任何联系。在其他被调查的药物中,只有酒精与对替代事实的信念呈负相关。总的来说,我们的研究结果支持了迷幻剂使用与非传统思维方式之间的联系,这可以归因于药物本身的心理效应,但也可能反映了与非传统信仰和非法药物使用相关的共同特征。