Arciniegas E, Blackstone E H, Pacifico A D, Kirklin J W
Ann Thorac Surg. 1979 Jun;27(6):514-8. doi: 10.1016/s0003-4975(10)63360-7.
One hundred forty-nine consecutive patients with tetralogy of Fallot, with or without pulmonary atresia, underwent Blalock-Taussig or Waterston operation for initial palliation. Of these patients, 45 were less than 6 months old, and 63 were less than 1 year old. The type of shunt, and the presence or absence of pulmonary atresia did not have a significant effect (p greater than 0.2) on hospital mortality. Parametric analysis showed a significant effect of age (p = 0.03), the risk of hospital death being 6% at 1 month of age, 4% at 3 months, 3% at 6 months, and 2.5% at 12 months. No late deaths occurred before the age of 3 years. Six patients (4.2% of the hospital survivors) required another operation before they were 3 years old. Severe arm ischemia occurred after a Blalock-Taussig shunt in 1 infant with Down's syndrome.
149例法洛四联症患者,无论有无肺动脉闭锁,均接受了Blalock-Taussig或Waterston手术进行初始姑息治疗。其中,45例患者年龄小于6个月,63例患者年龄小于1岁。分流类型以及有无肺动脉闭锁对住院死亡率无显著影响(p大于0.2)。参数分析显示年龄有显著影响(p = 0.03),1月龄时住院死亡风险为6%,3月龄时为4%,6月龄时为3%,12月龄时为2.5%。3岁前无晚期死亡病例。6例患者(占住院存活者的4.2%)在3岁前需要再次手术。1例患有唐氏综合征的婴儿在Blalock-Taussig分流术后出现严重的手臂缺血。