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COVID-19 大流行对成人非疑似死亡死后 CT 服务的影响。

Impact of the COVID-19 pandemic on a post-mortem CT service for adult non-suspicious death.

机构信息

Imaging Department, University Hospitals of Leicester, Leicester Royal Infirmary, Leicester LE2 7LX, UK.

The Coroner's Court, Town Hall, Town Hall Square, Leicester, UK.

出版信息

Clin Radiol. 2023 Nov;78(11):822-831. doi: 10.1016/j.crad.2023.03.013. Epub 2023 Aug 14.

Abstract

Due to the COVID-19 pandemic, the post-mortem computed tomography (PMCT) service was expanded from three to seven cases per day to help mortuary services and avoid invasive autopsy. Additional targeted angiography and pulmonary ventilation procedures were stopped and triage rules relaxed to allow more indications to be scanned, including those requiring toxicology. A service evaluation was performed for the first 3-months of the COVID-19 pandemic compared to the equivalent period the previous year to study the impact of these changes. It was found that, despite the increase in deaths regionally, coronial referrals remained about 100 per month, a reduction in referral rate. The number undergoing PMCT rose from 28% to 74% of cases. Turnaround time remained the same. For cases triaged to PMCT, the need for subsequent autopsy increased from 7.9% to 15.8%. No significant changes were seen in diagnosis rates, including cardiac or respiratory. There was an increase in patients with coronary death without severe coronary calcification who underwent autopsy after PMCT. These may have been diagnosed by targeted coronary angiography. Fifty-three cases requiring toxicology/biochemistry had PMCT, with 38 having PMCT only. In 8/11 (72.7%) cases with normal PMCT and toxicology as the key diagnostic test, autopsy was performed prior to results. This suggests the pathology team were reluctant to risk an "unascertained" outcome. This study shows that it is possible to increase PMCT services by widening referral criteria and by limiting the use of enhanced imaging techniques, without significantly changing diagnosis rates of key diseases; however, selectively restarting targeted angiography may help avoid autopsy in some cases.

摘要

由于 COVID-19 大流行,死后计算机断层扫描 (PMCT) 服务从每天 3 例扩展到 7 例,以帮助太平间服务并避免进行有创尸检。此外,还停止了针对性的血管造影和肺通气程序,并放宽了分诊规则,以允许更多的适应症进行扫描,包括需要毒理学检查的适应症。对 COVID-19 大流行的前 3 个月进行了服务评估,与前一年同期进行了比较,以研究这些变化的影响。结果发现,尽管该地区的死亡人数有所增加,但死因裁判官的转介仍约为每月 100 例,转介率有所下降。接受 PMCT 的人数从 28%增加到 74%。周转时间保持不变。对于分诊到 PMCT 的病例,随后进行尸检的需求从 7.9%增加到 15.8%。诊断率(包括心脏或呼吸)没有明显变化。接受 PMCT 后进行尸检的无严重冠状动脉钙化的冠状动脉死亡患者有所增加。这些患者可能通过针对性冠状动脉造影进行了诊断。有 53 例需要毒理学/生物化学检查的病例进行了 PMCT,其中 38 例仅进行了 PMCT。在 8/11(72.7%)例 PMCT 正常且毒理学作为关键诊断测试的病例中,在获得结果之前进行了尸检。这表明病理科团队不愿意冒险得出“不确定”的结果。本研究表明,通过放宽转诊标准和限制增强成像技术的使用,扩大 PMCT 服务是可行的,而不会显著改变关键疾病的诊断率;然而,选择性地重新启动针对性血管造影术可能有助于避免某些情况下的尸检。

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