Department of Cardiology, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Research and Training Hospital, İstanbul, Türkiye.
Department of Cardiology, Süreyyapaşa Chest Diseases and Thoracic Surgery Training and Research Hospital, İstanbul, Türkiye.
Anatol J Cardiol. 2024 Jan 2;28(1):29-34. doi: 10.14744/AnatolJCardiol.2023.3484. Epub 2023 Oct 16.
In this study, we aimed to investigate the clinical follow-up results of endoscopic thoracic sympathectomy (ETS) in the treatment of vasospastic angina (VSA) resistant to maximal medical therapy.
A total of 80 patients with VSA who presented to our hospital between 2010 and 2022 were included in our study. Among them, 6 patients who did not respond to medical therapy underwent ETS. In-hospital and long-term clinical outcomes of patients who underwent ETS were recorded.
The median age of the patients with VSA was 57 [48-66] years, and 70% of the group were males. In the ETS group, compared to the non-ETS group, higher numbers of hospital admissions and coronary angiographies were observed before ETS (median 6 [5-6] versus 2 [1-3], P <.001; median 5 [3-6] versus 2 [1-3], P =.004, respectively). Additionally, while 2 patients (33.3%) in the ETS group had implantable cardioverter defib-rillator (ICD), only 2 patients (2.7%) in the non-ETS group had ICD (P =.027). Out of the 6 patients who underwent ETS, 2 were females, with a median age of 56 [45-63] years. Four patients underwent successful bilateral ETS, while 2 patients underwent unilateral ETS. During the follow-up period after ETS, only 3 patients experienced sporadic attacks (once in 28 months, twice in 41 months, and once in 9 years, respectively), while no attacks were observed in 3 patients during their median follow-up of 7 years.
It appears that ETS is effective in preventing VSA attacks without any major complications.
本研究旨在探讨内镜胸交感神经切断术(ETS)治疗最大药物治疗抵抗性血管痉挛性心绞痛(VSA)的临床随访结果。
纳入 2010 年至 2022 年我院收治的 80 例 VSA 患者,其中 6 例药物治疗无反应患者行 ETS。记录 ETS 患者的住院和长期临床结局。
VSA 患者的中位年龄为 57 [48-66] 岁,70%为男性。在 ETS 组中,与非 ETS 组相比,在 ETS 前观察到更多的住院和冠状动脉造影(中位数 6 [5-6] 与 2 [1-3],P<0.001;中位数 5 [3-6] 与 2 [1-3],P=0.004)。此外,ETS 组有 2 例(33.3%)患者植入了植入式心脏复律除颤器(ICD),而非 ETS 组仅 2 例(2.7%)患者植入了 ICD(P=0.027)。在接受 ETS 的 6 例患者中,2 例为女性,中位年龄为 56 [45-63] 岁。4 例患者行双侧 ETS 成功,2 例患者行单侧 ETS。在 ETS 后随访期间,仅 3 例患者偶发发作(分别在 28 个月、41 个月和 9 年各 1 次),而 3 例患者在中位随访 7 年期间均无发作。
ETS 似乎可有效预防 VSA 发作,且无重大并发症。