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[伴发、异步性和难治性三叉神经痛与舌咽神经痛。单次手术治疗效果良好]

[Concomitant, asynchronous and refractory trigeminal and glossopharyngeal neuralgia. Good response to surgical approach in one time].

作者信息

Flores-Pina B, Paré-Curell M, Menéndez-Osorio B, Dorado-Bouix L

机构信息

Hospital Universitari Germans Trias i Pujol, 08916 Badalona, España.

出版信息

Rev Neurol. 2023 Nov 1;77(9):223-225. doi: 10.33588/rn.7709.2023182.

Abstract

INTRODUCTION

Microvascular decompression (MVD) surgery is the first choice treatment for refractory cranial neuralgia secondary to vascular compression. Simultaneous neuralgia of two cranial nerves is extremely rare. We describe a case of concomitant refractory trigeminal (TN) and glossopharyngeal (GN) neuralgia secondary to neurovascular crossover, treated surgically at the same time.

CASE REPORT

65-year-old woman with right TN (initially V2-V3) since 2004 with regular control with carboxamides. Seventeen years later, paroxysms worsened in V2-V3, also appearing in V1 and in the territory of the right glossopharyngeal nerve (right ear and tonsillar fossa when speaking and swallowing). Cerebral MRI showed significant arterial contact between the superior cerebellar artery (SCA) with the origin of the right V cranial nerve and the antero-inferior cerebellar artery (AICA) with the origin of the right lower CCNN. MVD of both cranial nerves was performed at the same surgical time by means of retrosigmoid craniectomy, releasing the V cranial nerve, in intimate contact with the SCA, and the IX cranial nerve in contact with the right AICA, interposing teflon between them. The patient had an immediate resolution of the trigeminal paroxysms and a dramatic improvement in intensity and frequency of glossopharyngeal paroxysms. Two years after the intervention, de-escalation of neuromodulator treatment continues with good response.

CONCLUSION

MVD in simultaneous TN and GN is feasible and can offer a good post-surgical outcome.

摘要

引言

微血管减压术(MVD)是治疗血管压迫所致难治性颅神经痛的首选方法。两条颅神经同时发生神经痛极为罕见。我们描述了一例因神经血管交叉导致的同时性难治性三叉神经痛(TN)和舌咽神经痛(GN)病例,并同时进行了手术治疗。

病例报告

一名65岁女性,自2004年起患有右侧TN(最初为V2 - V3),一直使用酰胺类药物定期控制。17年后,V2 - V3区域的发作加剧,V1区域以及右侧舌咽神经分布区域(说话和吞咽时右耳及扁桃体窝)也出现发作。脑部MRI显示小脑上动脉(SCA)与右侧V颅神经起始部之间以及小脑前下动脉(AICA)与右侧下部CCNN起始部之间存在明显的动脉接触。通过乙状窦后颅骨切除术在同一手术时间对两条颅神经进行MVD,松解与SCA紧密接触的V颅神经以及与右侧AICA接触的IX颅神经,并在它们之间置入聚四氟乙烯。患者三叉神经发作立即缓解,舌咽神经发作的强度和频率显著改善。干预两年后,神经调节剂治疗逐步减量,反应良好。

结论

同时进行TN和GN的MVD是可行的,并且可以提供良好的手术效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba27/10831735/b7ae7fd6d2f0/RN-77-223-g001.jpg

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