与肺非典型类癌肿瘤相关的副肿瘤性自身免疫性边缘叶脑炎：一例报告
Paraneoplastic Autoimmune Limbic Encephalitis Associated with an Atypical Carcinoid Tumor of the Lung: A Case Report.
作者信息
Marull Paretas Emma, De Vito Claudio, Catalano-Chiuve Sabina, Vargas Maria-Isabel, Assal Frédéric, Lalive Patrice, Bridel Claire
机构信息
Division of Neurology, Department of Neurosciences, Faculty of Medicine, Geneva University Hospitals, Geneva, Switzerland.
Division of Clinical Pathology, Geneva University Hospitals, Geneva, Switzerland.
出版信息
Case Rep Neurol. 2023 Jun 7;15(1):172-176. doi: 10.1159/000529846. eCollection 2023 Jan-Dec.
We report the case of a patient with a history of an atypical lung carcinoid tumor who developed a rapidly progressive memory impairment. The clinical presentation as well as brain MRI, cerebrospinal fluid, and laboratory tests led to the diagnosis of seronegative paraneoplastic autoimmune limbic encephalitis. To the best of our knowledge, this is the first case in literature of such association. This case also highlights an exceptionally favorable outcome, both clinically and radiologically, after immunosuppression and tumor removal.
我们报告了一例有非典型肺类癌肿瘤病史的患者，该患者出现了快速进展的记忆障碍。临床表现以及脑部磁共振成像、脑脊液和实验室检查结果确诊为血清阴性副肿瘤性自身免疫性边缘叶脑炎。据我们所知，这是文献中首例此类关联病例。该病例还凸显了免疫抑制和肿瘤切除后在临床和影像学方面均取得的格外良好的预后。
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