一名14岁男孩的唇部银屑病病例经阿达木单抗成功治疗

A Case of Lip Psoriasis in a 14-Year-Old Boy Successfully Treated with Adalimumab.

作者信息

Caroppo Francesca, Gnesotto Laura, Ludovica Deotto Maria, Salmaso Roberto, Fortina Anna Belloni

机构信息

Department of Medicine DIMED & Department of Women's and Children's Health SDB, Pediatric Dermatology Regional Center, University of Padova, Padova, Italy.

Department of Medicine DIMED, Surgical Pathology and Cytopathology Unit, University of Padova, Padova, Italy.

出版信息

Case Rep Dermatol. 2023 Sep 4;15(1):142-146. doi: 10.1159/000532103. eCollection 2023 Jan-Dec.

DOI:10.1159/000532103

PMID:37933229

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10625818/

Abstract

Psoriasis is a common chronic skin disease mainly located in areas of friction. Psoriasis of the lips as an exclusive presentation is rare and often misdiagnosed. Different anti-psoriatic therapies have been proposed, but the literature is limited to case studies with partial results. Biologic therapies have revolutionized the management of many dermatologic conditions, including psoriasis, and they are approved for pediatric use. We report the case of a 14-year-old boy with a 2-year history of white-yellowish scaling lesions on his lips, without intraoral involvement. Lip biopsy showed a psoriasiform pattern. Treatment with adalimumab 40 mg every other week was started, and after 6 months of therapy, we obtained a complete remission of the patient's lip psoriasis.

摘要

银屑病是一种常见的慢性皮肤病，主要位于易摩擦部位。以唇部为唯一表现的银屑病较为罕见，且常被误诊。目前已提出了不同的抗银屑病疗法，但相关文献仅限于部分结果的病例研究。生物疗法彻底改变了包括银屑病在内的许多皮肤病的治疗方式，并且已获批用于儿科治疗。我们报告了一名14岁男孩的病例，其唇部有2年的白黄色鳞屑性皮损病史，未累及口腔内部。唇部活检显示为银屑病样模式。开始每隔一周使用40毫克阿达木单抗进行治疗，经过6个月的治疗，患者唇部银屑病完全缓解。