Itou Junya, Munakata Yutaro, Kuramitsu Yujiro, Madarame Hiromi, Okazaki Ken
Department of Orthopaedic Surgery, Tokyo Women's Medical University, Tokyo, Japan.
Orthop Res Rev. 2023 Nov 3;15:199-205. doi: 10.2147/ORR.S430145. eCollection 2023.
Venous thromboembolism (VTE) is a potential major complication in patients undergoing total hip arthroplasty (THA). However, the incidence of VTE following THA using anterolateral supine approach (ALS) has not been reported. The purpose of this study was to investigate the incidence of perioperative VTE and the distribution and characteristics of deep vein thrombosis (DVT) following ALS THA.
This retrospective single-arm study analyzed the 182 consecutive hips of 164 patients who underwent primary ALS THA. Pharmacological prophylaxis consisted of enoxaparin 20 mg twice daily for approximately 6 days starting 24 h postoperatively until duplex ultrasonography was performed to determine whether postoperative DVT was present. DVT was assessed by whole-leg Doppler ultrasound, and the location and characteristics of any thrombus were recorded. If pulmonary thromboembolism was suspected, contrast-enhanced computed tomography was performed.
The overall incidence of VTE was 9.9% for DVT (18/182 hips) and 0.5% for pulmonary thromboembolism (1/182 hips). Most DVTs were in the soleal vein on the affected side and showed isoechoic or hypoechoic echogenicity. All thrombi were non-floating.
Following ALS THA with standard pharmacological prophylaxis and an early weight-bearing protocol, the incidence of perioperative DVT was approximately 10%, mostly occurring in the lower leg.
静脉血栓栓塞症(VTE)是全髋关节置换术(THA)患者潜在的主要并发症。然而,采用前外侧仰卧入路(ALS)进行THA后VTE的发生率尚未见报道。本研究的目的是调查ALS THA围手术期VTE的发生率以及深静脉血栓形成(DVT)的分布和特征。
这项回顾性单臂研究分析了164例接受初次ALS THA患者的182个连续髋关节。药物预防措施包括术后24小时开始使用依诺肝素20mg,每日两次,持续约6天,直至进行双功超声检查以确定术后是否存在DVT。通过全腿多普勒超声评估DVT,并记录任何血栓的位置和特征。如果怀疑有肺血栓栓塞,则进行增强CT检查。
VTE的总体发生率为DVT 9.9%(18/182个髋关节),肺血栓栓塞0.5%(1/182个髋关节)。大多数DVT位于患侧的比目鱼肌静脉,表现为等回声或低回声。所有血栓均无漂浮。
在采用标准药物预防和早期负重方案的ALS THA后,围手术期DVT的发生率约为10%,主要发生在小腿。