AlKhateeb Ahmed, Alrusayyis Danah
Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Imam Abdulrahman Bin Faisal University, King Faisal Ibn Abd Al Aziz, Al Safa, 34212, Dammam, Saudi Arabia.
Eur Arch Otorhinolaryngol. 2024 Mar;281(3):1331-1336. doi: 10.1007/s00405-023-08323-z. Epub 2023 Nov 9.
To evaluate the outcome of a routine postoperative endoscopic micro-debridement of granulation tissue after stentless transnasal endoscopic repair of choanal atresia (CA).
This prospective case series included congenital CA patients who underwent stentless transnasal endoscopic repair, followed by an endoscopic second look and micro-debridement of granulation tissue at 1-2 weeks post-repair. Patients were followed every three months for assessment of nasal airway symptoms and objective evaluation by flexible nasolaryngoscopy.
Sixteen CA patients (8 bilateral and 8 unilateral) underwent surgical repair (12 primary and 4 revisions). The median age was 13 days (range 1 day-6 months) in bilateral and 3 years (range 7 months-15 years) in unilateral atresia. The mean follow-up was 1.5 years (range 1 year-3 years). In primary procedures, the obstruction was bony-membranous in 7 cases and bony in 5 cases. The mean interval time between the CA repair and re-examination was 10.75 days (range 6-18 days). Clinically significant neochoanal restenosis was not encountered.
Re-examination under general anesthesia with endoscopic micro-debridement of granulation tissue is a safe, potentially effective adjunct when done during the proliferative phase of neochoanal wound healing. This procedure might help in maintaining neochoanal patency by remodeling tissue healing process. Large-scale, long-term cohort studies are imperative.
评估在无支架经鼻内镜修复后鼻孔闭锁(CA)术后常规进行内镜下肉芽组织微清创的效果。
本前瞻性病例系列研究纳入了接受无支架经鼻内镜修复的先天性CA患者,术后1 - 2周进行内镜二次探查及肉芽组织微清创。每三个月对患者进行随访,评估鼻气道症状,并通过软性鼻咽喉镜进行客观评估。
16例CA患者(8例双侧,8例单侧)接受了手术修复(12例初次手术,4例再次手术)。双侧闭锁患者的中位年龄为13天(范围1天 - 6个月),单侧闭锁患者为3岁(范围7个月 - 15岁)。平均随访时间为1.5年(范围1年 - 3年)。在初次手术中,7例阻塞为骨膜性,5例为骨性。CA修复与复查之间的平均间隔时间为10.75天(范围6 - 18天)。未出现具有临床意义的新后鼻孔再狭窄。
在新后鼻孔伤口愈合的增殖期进行全身麻醉下的内镜下肉芽组织微清创复查是一种安全、可能有效的辅助手段。该操作可能通过重塑组织愈合过程来帮助维持新后鼻孔通畅。大规模、长期的队列研究势在必行。