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使用时移测量法确定离体牛肝中的消融区

Determining of Ablation Zone in Ex Vivo Bovine Liver Using Time-Shift Measurements.

作者信息

Lamhamdi Mohamed, Esmaeili Ali, Layes Kiyan, El Maaroufi Zakaria, Rose Georg, Brensing Andreas, Schweizer Bernd

机构信息

Deparment of Engineering, RheinMain University of Applied Science, 65428 Rüsselsheim, Germany.

Institute of Medical Engineering and Research Campus STIMULATE, Otto Von Guericke University, 39106 Magdeburg, Germany.

出版信息

Cancers (Basel). 2023 Oct 31;15(21):5230. doi: 10.3390/cancers15215230.

Abstract

This study presents a measurement principle for determining the size of the ablation zone in MWA, which could ultimately form an alternative to more expensive monitoring approaches like CT. The measurement method is based on a microwave transmission measurement. A MWA is performed experimentally on ex vivo bovine liver to determine the ablation zone. This setup uses a custom slot applicator performing the MWA at an operating frequency of 2.45 GHz and a custom bowtie antenna measuring the waves transmitted from the applicator. Furthermore, a custom measurement probe is used to determine the dielectric properties. A time-shift analysis is used to determine the radial extent of the ablation zone. Several measurements are carried out with a power of 50 W for 10 min to show the reproducibility. The results show that this method can provide reproducible outcomes to determine the ablation zone with a maximum error of 4.11%.

摘要

本研究提出了一种用于确定微波消融(MWA)中消融区大小的测量原理,这最终可能成为像CT等更昂贵监测方法的替代方案。该测量方法基于微波传输测量。在离体牛肝上进行了MWA实验以确定消融区。此装置使用一个定制的缝隙施加器在2.45 GHz的工作频率下进行MWA,并使用一个定制的蝴蝶结天线测量从施加器传输的波。此外,使用一个定制的测量探头来确定介电特性。采用时移分析来确定消融区的径向范围。以50 W的功率进行10分钟的多次测量以显示其可重复性。结果表明,该方法能够提供可重复的结果来确定消融区,最大误差为4.11%。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4890/10650454/9e1e2d7787c8/cancers-15-05230-g001.jpg

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