Department of Nature and Life Sciences, University of Biskra, Biskra, Algeria.
Laboratory of Genetics, Biotechnology and Valorization of Bioresources, University of Biskra, Algeria.
Nat Prod Res. 2024 Dec;38(24):4355-4367. doi: 10.1080/14786419.2023.2282113. Epub 2023 Nov 16.
This study represents the first investigation of the chemical composition and the antioxidant and antimicrobial activities of Förther & Podlech, a plant species endemic to the Aures Mountains of Algeria. The essential oil of the plant aerial parts was analysed using GC-MS. The antioxidant activity was evaluated using three methods. A total of 44 compounds were identified. The major constituents were dodecanal, hexahydrofarnesylacetone, 2-tridecanone, phytol, 1-heneicosene, and -heneicosane. The oil displayed significant activity in the β-carotene bleaching assay, moderate scavenging activity against DPPH radicals and a low ability to reduce iron ions. Antibacterial tests conducted on four strains revealed effectiveness primarily against Gram-positive strains, specifically ATCC 25923 and ATCC 43300, while showing limited impact on Gram-negative strains, ATCC 27853 and ATCC 25922. Antifungal activity tests involving two moulds revealed a stronger inhibition against compared to
这项研究首次调查了阿尔及利亚欧雷斯山脉特有植物 Förther & Podlech 的化学成分、抗氧化和抗菌活性。采用 GC-MS 对植物地上部分的精油进行了分析。采用三种方法评估了抗氧化活性。共鉴定出 44 种化合物。主要成分是十二醛、六氢金合欢基丙酮、2-二十三酮、叶绿醇、1-二十一烯和二十一烷。该油在β-胡萝卜素漂白试验中表现出显著的活性,对 DPPH 自由基具有中等的清除活性,还原铁离子的能力较低。对四种菌株进行的抗菌试验表明,该油主要对革兰氏阳性菌株有效,特别是 ATCC 25923 和 ATCC 43300,而对革兰氏阴性菌株,即 ATCC 27853 和 ATCC 25922 的影响有限。对两种霉菌的抗真菌活性试验表明,与 相比,该油对 的抑制作用更强。