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首次报道了阿尔及利亚特有植物的精油的化学成分、自由基清除活性和抗菌活性。

First report on the chemical composition and the free radical scavenging and antimicrobial activities of the essential oil of , an endemic plant of Algeria.

机构信息

Department of Nature and Life Sciences, University of Biskra, Biskra, Algeria.

Laboratory of Genetics, Biotechnology and Valorization of Bioresources, University of Biskra, Algeria.

出版信息

Nat Prod Res. 2024 Dec;38(24):4355-4367. doi: 10.1080/14786419.2023.2282113. Epub 2023 Nov 16.

Abstract

This study represents the first investigation of the chemical composition and the antioxidant and antimicrobial activities of Förther & Podlech, a plant species endemic to the Aures Mountains of Algeria. The essential oil of the plant aerial parts was analysed using GC-MS. The antioxidant activity was evaluated using three methods. A total of 44 compounds were identified. The major constituents were dodecanal, hexahydrofarnesylacetone, 2-tridecanone, phytol, 1-heneicosene, and -heneicosane. The oil displayed significant activity in the β-carotene bleaching assay, moderate scavenging activity against DPPH radicals and a low ability to reduce iron ions. Antibacterial tests conducted on four strains revealed effectiveness primarily against Gram-positive strains, specifically ATCC 25923 and ATCC 43300, while showing limited impact on Gram-negative strains, ATCC 27853 and ATCC 25922. Antifungal activity tests involving two moulds revealed a stronger inhibition against compared to

摘要

这项研究首次调查了阿尔及利亚欧雷斯山脉特有植物 Förther & Podlech 的化学成分、抗氧化和抗菌活性。采用 GC-MS 对植物地上部分的精油进行了分析。采用三种方法评估了抗氧化活性。共鉴定出 44 种化合物。主要成分是十二醛、六氢金合欢基丙酮、2-二十三酮、叶绿醇、1-二十一烯和二十一烷。该油在β-胡萝卜素漂白试验中表现出显著的活性,对 DPPH 自由基具有中等的清除活性,还原铁离子的能力较低。对四种菌株进行的抗菌试验表明,该油主要对革兰氏阳性菌株有效,特别是 ATCC 25923 和 ATCC 43300,而对革兰氏阴性菌株,即 ATCC 27853 和 ATCC 25922 的影响有限。对两种霉菌的抗真菌活性试验表明,与 相比,该油对 的抑制作用更强。

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