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以出血为首发表现的下颌骨棕色巨细胞瘤:一例报告

Large Brown Tumour of Mandible with Bleeding as Initial Presentation: A Case Report.

作者信息

Pawar Ajinkya, Rathod Priyank, Aaron Jebin, Bande Vivek, Kapur Kanika

机构信息

Mch Surgical oncology, GCRI hospital, Ahmedabad, MS General surgery, DNB General surgery, 80B/42, Brindavan Society, Thane West, Maharashtra, 400601 India.

Surgical oncology, GCRI hospital, Ahmedabad, MS Mch Head and Neck oncosurgery, 1, Krushnapark Society, Karelibaig,, Vadodara, Gujarat 390018 India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2023 Dec;75(4):3988-3992. doi: 10.1007/s12070-023-04003-w. Epub 2023 Jun 30.

Abstract

Brown Tumour or Osteitis fibrous cystic or Von-Recklinghausen disease of bone is a non-malignant condition due to abnormal metabolism of bones in hyperparathyroidism. Although pathognomonic of hyperparathyroidism, brown tumours are rare and only case reports are found in literature. We report a case of brown tumour of mandible with recurrent episodes of bleeding. A 46 year old male patient presented in emergency with bleeding from ulceroproliferative mass from left floor of mouth. After control of bleeding, radiological, laboratory and histopathological investigations were done that led to the diagnosis of brown tumour of mandible in the presence of parathyroid adenoma of left lower parathyroid gland. Left upper and lower parthyroidectomy was done with segmental resection of mandible with mass and titanium plating. Brown tumour of facial bones is a rare entity. Very rarely it can reach enormous sizes to cause bleeding. Although parathyroidectomy and correction of parathormone levels cause regression of small tumours, large brown tumours with complications should be managed with surgical resection and reconstruction.

摘要

棕色瘤或骨纤维囊性骨炎或骨的冯·雷克林霍增氏病是一种由于甲状旁腺功能亢进导致骨骼代谢异常引起的非恶性病症。尽管棕色瘤是甲状旁腺功能亢进的特征性表现,但较为罕见,文献中仅有病例报告。我们报告一例下颌骨棕色瘤伴反复出血病例。一名46岁男性患者因左口底溃疡性增生性肿物出血急诊就诊。出血得到控制后,进行了影像学、实验室及组织病理学检查,结果在左下甲状旁腺腺瘤存在的情况下诊断为下颌骨棕色瘤。行左上下甲状旁腺切除术,同时切除下颌骨肿物并行钛板内固定。面骨棕色瘤是一种罕见疾病。极少情况下其可长得非常大并导致出血。尽管甲状旁腺切除术及甲状旁腺激素水平的纠正可使小肿瘤消退,但对于有并发症的大棕色瘤应行手术切除及重建治疗。

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本文引用的文献

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