台湾地区阿尔茨海默病患者及其知情人的 12 年比较
A 12-Year Comparison of Alzheimer's Dementia Patients With Their Informants in Taiwan.
机构信息
Department of Neurology, Changhua Christian Hospital, Changhua, Taiwan.
Department of Neurology, Taitung MacKay Memorial Hospital, Taitung, Taiwan.
出版信息
Am J Alzheimers Dis Other Demen. 2023 Jan-Dec;38:15333175231218089. doi: 10.1177/15333175231218089.
BACKGROUND
To update the characteristics of patients with Alzheimer's disease (AD) and their informants in Taiwan and compare them from 12 years ago.
METHODS
1218 patients with AD and their informants were recruited from six hospitals in Taiwan. The uniform data set version 3.0 (UDS3, form A1-A3) were administered.
RESULTS
Compared with the first registration from 2010-2012 (n = 691), the mean clinical dementia rating sum of boxes score was significantly lower, more patients living independently, and more informants not living together with the patients. A total of 11.2%, 4.1%, 12.8%, and 0.5% of the patients had a reported history of cognitive impairment in their mothers, fathers, siblings, and children, respectively.
CONCLUSION
Compared with the data from 2010, patients have been diagnosed at a milder disease stage, and their informants used telephone contact more frequently instead of living with the patients. Family histories of cognitive impairment in patients with AD remain frequent.
背景
更新台湾地区阿尔茨海默病（AD）患者及其照料者的特征，并将其与 12 年前的数据进行比较。
方法
从台湾的六家医院招募了 1218 名 AD 患者及其照料者。使用统一数据采集表 3.0 版（UDS3，A1-A3 表单）进行评估。
结果
与 2010-2012 年的首次登记（n=691）相比，患者的临床痴呆评定量表总评分明显较低，更多的患者独立生活，更多的照料者不和患者住在一起。分别有 11.2%、4.1%、12.8%和 0.5%的患者报告其母亲、父亲、兄弟姐妹和子女有认知障碍病史。
结论
与 2010 年的数据相比，患者的诊断处于更轻度的疾病阶段，其照料者更多地使用电话联系而不是与患者住在一起。AD 患者的认知障碍家族史仍然较为常见。
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