Department of Neurology, Nagano Municipal Hospital, Japan.
Department of Neurology, Ina Central Hospital, Japan.
Intern Med. 2024 Jul 15;63(14):2083-2087. doi: 10.2169/internalmedicine.2092-23. Epub 2023 Dec 4.
Alice in Wonderland syndrome (AIWS) is extremely rare, occurring more often in young individuals than in older adults. Symptoms of this syndrome typically include an altered body image, size perception, and time perception. However, the pathophysiology and lesions responsible for this syndrome remain unclear. In most cases, specific lesions cannot be identified using computed tomography or magnetic resonance imaging. Two patients with isolated cortical venous thrombosis in the right occipital area experienced transient visual symptoms of AIWS. Furthermore, a literature search indicated that AIWS with visual distortions is associated with right occipital lobe lesions, supporting the findings of our study.
爱丽丝梦游仙境综合征(AIWS)极为罕见,多见于年轻人,而在老年人中较少见。该综合征的症状通常包括身体形象、大小感知和时间感知的改变。然而,该综合征的病理生理学和相关病变仍不清楚。在大多数情况下,计算机断层扫描或磁共振成像无法确定特定的病变。两名右侧枕叶孤立性皮质静脉血栓形成的患者出现短暂的 AIWS 视觉症状。此外,文献检索表明,伴有视觉扭曲的 AIWS 与右侧枕叶病变有关,这支持了我们的研究结果。