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成人腹部枪伤选择性非手术治疗的结局:系统评价和荟萃分析。

Outcomes of selective non-operative management in adults with abdominal gunshot wounds: a systematic review and meta-analysis.

机构信息

Military Medical Research Group, General Hospital of Northern Theater Command, Shenyang, Liaoning Province.

Meta-Analysis Interest Group, Department of Gastroenterology, General Hospital of Northern Theater Command.

出版信息

Int J Surg. 2024 Feb 1;110(2):1183-1195. doi: 10.1097/JS9.0000000000000915.

Abstract

BACKGROUND AND AIMS

Abdominal gunshot wounds (GSWs), a clinically devastating injury, can result in a variety of severe and lethal complications. Traditionally, exploratory laparotomy is the first-line approach for the management of abdominal GSWs, but it is associated with a considerable amount of unnecessary surgeries. At present, selective non-operative management (SNOM) of abdominal GSWs is becoming an effective and well-recognized approach, but it remains widely disputed since many surgeons are skeptical about the validity of SNOM in clinical practice. This meta-analysis aims to estimate the outcomes of SNOM and immediate laparotomy in patients with GSWs by collecting the currently available evidence.

METHODS

The PubMed , EMBASE , and Cochrane Library databases were searched. A random-effects model was employed. A pooled proportion with 95% confidence intervals (CIs) was calculated. Heterogeneity was evaluated using Cochran's Q test and I2 statistics.

RESULTS

Overall, 53 studies involving 60 291 participants were included. The pooled proportions of SNOM and SNOM failure were 27.0% (95% CI=24.0-30.0%) and 10.0% (95% CI=7.0-13.0%), respectively. The pooled mortality after SNOM and SNOM failure were 0.0% (95% CI=0.0-1.0%) and 0.0% (95% CI=0.0-0.0%), respectively. The pooled proportions of immediate laparotomy and unnecessary immediate laparotomy were 73.0% (95% CI=70.0-76.0%) and 10.0% (95% CI=8.0-13.0%), respectively. The pooled mortality after immediate laparotomy and unnecessary immediate laparotomy was 10.0% (95% CI=8.0-13.0%) and 0.0% (95% CI=0.0-1.0%), respectively. Heterogeneity was statistically significant in nearly all meta-analyses.

CONCLUSION

Immediate laparotomy is still the mainstay approach for the management of abdominal GSWs. Approximately one-third of patients with abdominal GSWs undergo SNOM. SNOM failure is not frequent, and its related mortality is also rare.

摘要

背景与目的

腹部枪伤(GSW)是一种具有临床破坏性的损伤,可导致多种严重和致命的并发症。传统上,剖腹探查术是治疗腹部 GSW 的首选方法,但它与大量不必要的手术有关。目前,选择性非手术治疗(SNOM)已成为治疗腹部 GSW 的一种有效且公认的方法,但由于许多外科医生对 SNOM 在临床实践中的有效性持怀疑态度,因此仍然存在广泛争议。本荟萃分析旨在通过收集现有证据来评估 SNOM 和腹部 GSW 患者立即剖腹手术的结果。

方法

检索了 PubMed、EMBASE 和 Cochrane Library 数据库。采用随机效应模型。计算了合并比例及其 95%置信区间(CI)。使用 Cochran's Q 检验和 I2 统计量评估异质性。

结果

共纳入 53 项研究,涉及 60291 名参与者。SNOM 和 SNOM 失败的合并比例分别为 27.0%(95%CI=24.0-30.0%)和 10.0%(95%CI=7.0-13.0%)。SNOM 后和 SNOM 失败后的死亡率分别为 0.0%(95%CI=0.0-1.0%)和 0.0%(95%CI=0.0-0.0%)。立即剖腹手术和不必要的立即剖腹手术的合并比例分别为 73.0%(95%CI=70.0-76.0%)和 10.0%(95%CI=8.0-13.0%)。立即剖腹手术后和不必要的立即剖腹手术后的死亡率分别为 10.0%(95%CI=8.0-13.0%)和 0.0%(95%CI=0.0-1.0%)。几乎所有的荟萃分析都存在统计学上的显著异质性。

结论

立即剖腹手术仍然是治疗腹部 GSW 的主要方法。大约三分之一的腹部 GSW 患者接受 SNOM。SNOM 失败并不常见,其相关死亡率也很低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de54/10871643/6b82ca070b19/js9-110-1183-g001.jpg

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