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创伤性脑损伤对酗酒者神经心理缺陷的影响。

Contribution of traumatic head injury to neuropsychological deficits in alcoholics.

作者信息

Hillbom M, Holm L

出版信息

J Neurol Neurosurg Psychiatry. 1986 Dec;49(12):1348-53. doi: 10.1136/jnnp.49.12.1348.

Abstract

The contribution of head injuries to neuropsychological deficits was studied in 157 recently detoxified alcoholics and 400 control subjects consisting of age-stratified randomly selected men and women from the same geographical area as the alcoholics. Head injuries had occurred in 41% and 22% of the male and female alcoholics, but only in 15% and 6% of the male and female control subjects. One third of the injured subjects in both groups had been admitted to hospital for treatment of the acute injury. The neuropsychological test results of alcoholics were significantly inferior to those of control subjects. Unexpectedly, alcoholics with head injuries not identified at hospital were significantly inferior in several Halstead-Reitan subtests when compared with uninjured alcoholics with a similar duration of alcoholism and abstinence. By contrast, control subjects who had sustained a head injury not identified at hospital did not show signs of intellectual impairment when compared with uninjured controls. We conclude that traumatic brain injuries that may cause significant intellectual impairment may easily remain unrecognised in alcoholics.

摘要

对157名近期戒酒的酗酒者和400名对照者进行了研究,以探讨头部损伤对神经心理缺陷的影响。对照者是从与酗酒者来自同一地理区域的人群中按年龄分层随机选取的男性和女性。男性和女性酗酒者中分别有41%和22%曾遭受头部损伤,而男性和女性对照者中这一比例仅为15%和6%。两组中三分之一的受伤者因急性损伤入院治疗。酗酒者的神经心理测试结果显著低于对照者。出乎意料的是,与酒精中毒和戒酒时间相似的未受伤酗酒者相比,在医院未被诊断出头部受伤的酗酒者在多项霍尔斯特德-赖坦分测验中表现明显较差。相比之下,在医院未被诊断出头部受伤的对照者与未受伤的对照者相比,没有表现出智力受损的迹象。我们得出结论,可能导致严重智力损伤的创伤性脑损伤在酗酒者中很容易被忽视。

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