Huang Hung-Yi, Hsiao Yu-Ping, Karmakar Riya, Mukundan Arvind, Chaudhary Pramod, Hsieh Shang-Chin, Wang Hsiang-Chen
Department of Dermatology, Ditmanson Medical Foundation Chiayi Christian Hospital, Chia Yi City 60002, Taiwan.
Department of Dermatology, Chung Shan Medical University Hospital, No.110, Sec. 1, Jianguo N. Rd., South District, Taichung City 40201, Taiwan.
Cancers (Basel). 2023 Nov 29;15(23):5634. doi: 10.3390/cancers15235634.
Skin cancer, a malignant neoplasm originating from skin cell types including keratinocytes, melanocytes, and sweat glands, comprises three primary forms: basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and malignant melanoma (MM). BCC and SCC, while constituting the most prevalent categories of skin cancer, are generally considered less aggressive compared to MM. Notably, MM possesses a greater capacity for invasiveness, enabling infiltration into adjacent tissues and dissemination via both the circulatory and lymphatic systems. Risk factors associated with skin cancer encompass ultraviolet (UV) radiation exposure, fair skin complexion, a history of sunburn incidents, genetic predisposition, immunosuppressive conditions, and exposure to environmental carcinogens. Early detection of skin cancer is of paramount importance to optimize treatment outcomes and preclude the progression of disease, either locally or to distant sites. In pursuit of this objective, numerous computer-aided diagnosis (CAD) systems have been developed. Hyperspectral imaging (HSI), distinguished by its capacity to capture information spanning the electromagnetic spectrum, surpasses conventional RGB imaging, which relies solely on three color channels. Consequently, this study offers a comprehensive exploration of recent CAD investigations pertaining to skin cancer detection and diagnosis utilizing HSI, emphasizing diagnostic performance parameters such as sensitivity and specificity.
皮肤癌是一种起源于包括角质形成细胞、黑素细胞和汗腺等皮肤细胞类型的恶性肿瘤,主要包括三种形式:基底细胞癌(BCC)、鳞状细胞癌(SCC)和恶性黑色素瘤(MM)。BCC和SCC虽然是最常见的皮肤癌类型,但与MM相比,通常被认为侵袭性较小。值得注意的是,MM具有更强的侵袭能力,能够浸润到邻近组织,并通过循环系统和淋巴系统扩散。与皮肤癌相关的危险因素包括紫外线(UV)辐射暴露、白皙的肤色、晒伤史、遗传易感性、免疫抑制状况以及接触环境致癌物。皮肤癌的早期检测对于优化治疗效果和防止疾病在局部或远处进展至关重要。为了实现这一目标,已经开发了许多计算机辅助诊断(CAD)系统。高光谱成像(HSI)以其能够捕获跨越电磁光谱的信息而著称,优于仅依赖三个颜色通道的传统RGB成像。因此,本研究全面探讨了利用HSI进行皮肤癌检测和诊断的近期CAD研究,重点关注敏感性和特异性等诊断性能参数。