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巴西巴伊亚州一家野外诊所的播散性皮肤利什曼病:8例报告

Disseminated cutaneous leishmaniasis in a field clinic in Bahia, Brazil: a report of eight cases.

作者信息

Costa J M, Marsden P D, Llanos-Cuentas E A, Netto E M, Carvalho E M, Barral A, Rosa A C, Cuba C C, Magalhães A V, Barreto A C

出版信息

J Trop Med Hyg. 1986 Dec;89(6):319-23.

PMID:3806749
Abstract

Eight Bahian patients with cutaneous leishmaniasis who had 20 or more ulcerative lesions of short duration are described. Of five identifications of isolated parasites, four were Leishmania braziliensis braziliensis and one was L. mexicana amazonensis. All but one had positive Montenegro tests initially, and all did after treatment. All had circulating anti-leishmanial antibodies and five responded well to glucantime therapy suggesting a functioning immune response. This is quite different to the anergic hansenoid leishmaniasis seen with L. mexicana amazonensis infections in Brazil. Possible reasons for the occurrence of this type of leishmaniasis are briefly discussed.

摘要

本文描述了8名巴伊亚州皮肤利什曼病患者,他们有20个或更多病程较短的溃疡性病变。在对分离出的寄生虫进行的5次鉴定中,4次鉴定为巴西利什曼原虫巴西亚种,1次鉴定为墨西哥利什曼原虫亚马逊亚种。除1人外,所有人最初的蒙氏试验均为阳性,治疗后全部转为阳性。所有人都有循环抗利什曼原虫抗体,5人对葡糖胺锑钠治疗反应良好,提示免疫反应正常。这与巴西墨西哥利什曼原虫亚马逊亚种感染所见的无反应性类鼻疽样利什曼病截然不同。本文简要讨论了这种类型利什曼病发生的可能原因。

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