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基于 CT 图像的腰椎管狭窄症深度学习模型的建立。

Development of a Deep-Learning Model for Diagnosing Lumbar Spinal Stenosis Based on CT Images.

机构信息

Department of Spine Surgery, Zhejiang Spine Research Center, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.

出版信息

Spine (Phila Pa 1976). 2024 Jun 15;49(12):884-891. doi: 10.1097/BRS.0000000000004903. Epub 2023 Dec 19.

Abstract

STUDY DESIGN

Retrospective study.

OBJECTIVES

This study aimed to develop an initial deep-learning (DL) model based on computerized tomography (CT) scans for diagnosing lumbar spinal stenosis.

SUMMARY OF BACKGROUND DATA

Magnetic resonance imaging is commonly used for diagnosing lumbar spinal stenosis due to its high soft tissue resolution, but CT is more portable, cost-effective, and has wider regional coverage. Using DL models to improve the accuracy of CT diagnosis can effectively reduce missed diagnoses and misdiagnoses in clinical practice.

MATERIALS AND METHODS

Axial lumbar spine CT scans obtained between March 2022 and September 2023 were included. The data set was divided into a training set (62.3%), a validation set (22.9%), and a control set (14.8%). All data were labeled by two spine surgeons using the widely accepted grading system for lumbar spinal stenosis. The training and validation sets were used to annotate the regions of interest by the two spine surgeons. First, a region of interest detection model and a convolutional neural network classifier were trained using the training set. After training, the model was preliminarily evaluated using a validation set. Finally, the performance of the DL model was evaluated on the control set, and a comparison was made between the model and the classification performance of specialists with varying levels of experience.

RESULTS

The central stenosis grading accuracies of DL Model Version 1 and DL Model Version 2 were 88% and 83%, respectively. The lateral recess grading accuracies of DL Model Version 1 and DL Model Version 2 were 75% and 71%, respectively.

CONCLUSIONS

Our preliminarily developed DL system for assessing the degree of lumbar spinal stenosis in CT, including the central canal and lateral recess, has shown similar accuracy to experienced specialist physicians. This holds great value for further development and clinical application.

摘要

研究设计

回顾性研究。

目的

本研究旨在开发一种基于计算机断层扫描(CT)的腰椎椎管狭窄症诊断深度学习(DL)模型。

背景资料概要

磁共振成像(MRI)由于软组织分辨率高,常用于诊断腰椎椎管狭窄症,但 CT 更便携、更具成本效益且覆盖范围更广。使用 DL 模型提高 CT 诊断的准确性可以有效减少临床实践中的漏诊和误诊。

材料和方法

纳入 2022 年 3 月至 2023 年 9 月获得的轴向腰椎 CT 扫描。数据集分为训练集(62.3%)、验证集(22.9%)和对照组(14.8%)。所有数据均由两位脊柱外科医生使用广泛接受的腰椎椎管狭窄分级系统进行标记。训练集和验证集用于由两位脊柱外科医生标注感兴趣区域。首先,使用训练集训练感兴趣区域检测模型和卷积神经网络分类器。训练后,使用验证集初步评估模型。最后,在对照组上评估 DL 模型的性能,并比较模型与不同经验水平的专家的分类性能。

结果

DL 模型版本 1 和 DL 模型版本 2 的中央狭窄分级准确率分别为 88%和 83%。DL 模型版本 1 和 DL 模型版本 2 的侧隐窝分级准确率分别为 75%和 71%。

结论

我们初步开发的用于评估 CT 中腰椎椎管狭窄程度(包括中央椎管和侧隐窝)的 DL 系统,其准确性与经验丰富的专科医生相似。这对于进一步开发和临床应用具有重要价值。

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