Department of Pediatrics, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Department of Pediatric Cardiovasology, Children's Medical Center, The Second Xiangya Hospital, Central South University, No.139 Renmin Middle Road, Changsha, 410011, Hunan, China.
Sci Rep. 2023 Dec 20;13(1):22724. doi: 10.1038/s41598-023-49722-w.
This research proposed to retrospectively analyze 20 years of clinical data and investigate the relationship between demographic factors and syncopal symptom in pediatric vasovagal syncope. A total of 2513 children, 1124 males and 1389 females, age range 3-18 years, who presented to Department of Pediatric Cardiovasology, Children's Medical Center, The Second Xiangya Hospital, Central South University with unexplained syncope or pre-syncope and were diagnosed with vasovagal syncope were retrospectively collected and divided into syncope group (n = 1262) and pre-syncope group (n = 1251). (1) Females had a 36% increased risk of syncope compared to males, a 27% increased risk of syncope for every 1-year increase in age, and a 2% decreased risk of syncope for every 1 cm increase in height. (2) A non-linear relationship between age, height, weight and syncope was observed. When age > 10.67 years, the risk of syncope increases by 45% for each 1-year increase in age; when height < 146 cm, the risk of syncope decreases by 4% for each 1 cm increase in height; when weight < 28.5 kg, the risk of syncope decreases by 10% for each 1 kg increase in weight. Demographic factors are strongly associated with syncopal symptom in pediatric vasovagal syncope and can help to predict the risk.
本研究拟回顾性分析 20 年临床资料,探讨小儿血管迷走性晕厥患者人口统计学因素与晕厥症状的关系。回顾性收集 2001 年 1 月至 2021 年 12 月在中南大学湘雅二医院儿童心血管科就诊的以不明原因晕厥或先兆晕厥为主要表现、诊断为血管迷走性晕厥的 2513 例患儿临床资料,其中男 1124 例,女 1389 例,年龄 3~18 岁。将患儿分为晕厥组(n=1262)和先兆晕厥组(n=1251)。(1)女性患儿发生晕厥的风险较男性增加 36%,年龄每增加 1 岁,发生晕厥的风险增加 27%,身高每增加 1cm,发生晕厥的风险降低 2%。(2)年龄、身高、体重与晕厥的关系呈非线性。当年龄>10.67 岁时,年龄每增加 1 岁,发生晕厥的风险增加 45%;身高<146cm 时,身高每增加 1cm,发生晕厥的风险降低 4%;体重<28.5kg 时,体重每增加 1kg,发生晕厥的风险降低 10%。人口统计学因素与小儿血管迷走性晕厥患者的晕厥症状密切相关,有助于预测风险。