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一期后路蛋壳截骨联合长节段椎弓根螺钉内固定治疗强直性脊柱炎后凸畸形合并急性胸腰椎椎体骨折的疗效

[Effectiveness of one-stage posterior eggshell osteotomy and long-segment pedicle screw fixation for ankylosing spondylitis kyphosis combined with acute thoracolumbar vertebral fracture].

作者信息

Zhang Yadong, Wang Wentao, Zhang Haiping, Li Houkun, Xue Xukai, Shan Lequn, Hao Dingjun

机构信息

Xi'an Medical University, Xi'an Shaanxi, 710068, P. R. China.

Department of Spine Surgery, Xi'an Jiaotong University Affiliated Honghui Hospital, Xi'an Shaanxi, 710054, P. R. China.

出版信息

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2023 Dec 15;37(12):1489-1495. doi: 10.7507/1002-1892.202307021.

Abstract

OBJECTIVE

To explore the safety and effectiveness of one-stage posterior eggshell osteotomy and long-segment pedicle screw fixation in the treatment of ankylosing spondylitis kyphosis combined with acute thoracolumbar vertebral fracture.

METHODS

A clinical data of 20 patients with ankylosing spondylitis kyphosis combined with acute thoracolumbar spine fracture, who were treated with one-stage posterior eggshell osteotomy and long-segment pedicle screw fixation between April 2016 and January 2022, was retrospectively analyzed. Among them, 16 cases were male and 4 cases were female; their ages ranged from 32 to 68 years, with an average of 45.9 years. The causes of injury included 10 cases of sprain, 8 cases of fall, and 2 cases of falling from height. The time from injury to operation ranged from 1 to 12 days, with an average of 7.1 days. The injured segment was T in 2 cases, T in 2 cases, L in 6 cases, and L in 10 cases. X-ray film and CT showed that the patients had characteristic imaging manifestations of ankylosing spondylitis, and the fracture lines were involved in the anterior, middle, and posterior columns and accompanied by different degrees of kyphosis and vertebral compression; and MRI showed that 12 patients had different degrees of nerve injuries. The operation time, intraoperative bleeding, intra- and post-operative complications were recorded. The visual analogue scale (VAS) score and Oswestry disability index (ODI) were used to evaluate the low back pain and quality of life, and the American spinal cord injury association (ASIA) classification was used to evaluate the neurological function. X-ray films were taken, and local Cobb angle (LCA) and sagittal vertical axis (SVA) were measured to evaluate the correction of the kyphosis.

RESULTS

All operations were successfully completed and the operation time ranged from 127 to 254 minutes (mean, 176.3 minutes). The amount of intraoperative bleeding ranged from 400 to 950 mL (mean, 722.5 mL). One case of dural sac tear occurred during operation, and no cerebrospinal fluid leakage occurred after repair, and the rest of the patients did not suffer from neurological and vascular injuries, cerebrospinal fluid leakage, and other related complications during operation. All incisions healed by first intention without infection or fat liquefaction. All patients were followed up 8-16 months (mean, 12.5 months). The VAS score, ODI, LCA, and SVA at 3 days after operation and last follow-up significantly improved when compared with those before operation ( <0.05), and the difference between 3 days after operation and last follow-up was not significant ( >0.05). The ASIA grading of neurological function at last follow-up also significantly improved when compared with that before operation ( <0.05), including 17 cases of grade E and 3 cases of grade D. At last follow-up, all bone grafts achieved bone fusion, and no complications such as loosening, breaking of internal fixation, and pseudoarthrosis occurred.

CONCLUSION

One-stage posterior eggshell osteotomy and long-segment pedicle screw fixation is an effective surgical procedure for ankylosing spondylitis kyphosis combined with acute thoracolumbar vertebral fracture. It can significantly relieve patients' clinical symptoms and to some extent, alleviate the local kyphotic deformity.

摘要

目的

探讨一期后路蛋壳截骨术联合长节段椎弓根螺钉内固定治疗强直性脊柱炎后凸畸形合并急性胸腰椎椎体骨折的安全性和有效性。

方法

回顾性分析2016年4月至2022年1月采用一期后路蛋壳截骨术联合长节段椎弓根螺钉内固定治疗的20例强直性脊柱炎后凸畸形合并急性胸腰椎椎体骨折患者的临床资料。其中男性16例,女性4例;年龄32~68岁,平均45.9岁。受伤原因包括扭伤10例,坠落8例,高处坠落2例。受伤至手术时间1~12天,平均7.1天。受伤节段:T10 2例,T11 2例,L1 6例,L2 10例。X线片及CT显示患者有强直性脊柱炎特征性影像学表现,骨折线累及前、中、后柱,伴有不同程度的后凸畸形及椎体压缩;MRI显示12例患者有不同程度神经损伤。记录手术时间、术中出血量、术中和术后并发症。采用视觉模拟评分法(VAS)和Oswestry功能障碍指数(ODI)评估腰痛及生活质量,采用美国脊髓损伤协会(ASIA)分级评估神经功能。拍摄X线片,测量局部Cobb角(LCA)和矢状垂直轴(SVA)评估后凸畸形矫正情况。

结果

所有手术均顺利完成,手术时间127~254分钟(平均176.3分钟)。术中出血量400~950毫升(平均722.5毫升)。术中发生1例硬脊膜撕裂,修补后未发生脑脊液漏,其余患者术中未发生神经及血管损伤、脑脊液漏等相关并发症。所有切口均一期愈合,无感染及脂肪液化。所有患者均获随访8~16个月(平均12.5个月)。术后3天及末次随访时VAS评分、ODI、LCA及SVA与术前比较均显著改善(P<0.05),术后3天与末次随访比较差异无统计学意义(P>0.05)。末次随访时神经功能ASIA分级与术前比较也显著改善(P<0.05),其中E级17例,D级3例。末次随访时所有植骨均达骨融合,未发生内固定松动、断裂及假关节等并发症。

结论

一期后路蛋壳截骨术联合长节段椎弓根螺钉内固定是治疗强直性脊柱炎后凸畸形合并急性胸腰椎椎体骨折的有效手术方法,能显著缓解患者临床症状,在一定程度上减轻局部后凸畸形。

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本文引用的文献

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Minimally Invasive Surgery for Thoracolumbar Spinal Fractures in Patients With Ankylosing Spondylitis.
Int J Spine Surg. 2023 Aug;17(4):526-533. doi: 10.14444/8478. Epub 2023 Jun 2.
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Percutaneous, PMMA-augmented, pedicle screw instrumentation of thoracolumbar ankylotic spine fractures.
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PLoS One. 2021 Apr 9;16(4):e0250009. doi: 10.1371/journal.pone.0250009. eCollection 2021.
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One-level mini-open pedicle subtraction osteotomy for treating spinal kyphosis in patients with ankylosing spondylitis.
BMC Musculoskelet Disord. 2021 Jan 22;22(1):101. doi: 10.1186/s12891-021-03974-7.

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