Zhang Shengruo, Kwach Benn, Omollo Victor, Asewe Magdaline, Malen Rachel C, Shah Parth D, Odoyo Josephine, Mugo Nelly, Ngure Kenneth, Bukusi Elizabeth A, Ortblad Katrina F
Department of Epidemiology, University of Washington, Seattle, WA 98195, USA.
Centre for Microbiology Research, Kenya Medical Research Institute, Nairobi 00200, Kenya.
Vaccines (Basel). 2023 Dec 2;11(12):1808. doi: 10.3390/vaccines11121808.
Vaccine coverage for the human papillomavirus (HPV) remains low globally, and differentiated models of vaccine delivery are needed to expand access. Pharmacy-based models of the HPV vaccination may engage women who could benefit. We assessed the acceptability of such a model among pharmacy clients and providers at 20 private pharmacies in Kisumu County, Kenya. In questionnaires, participants (≥18 years) were asked the extent they agreed (5-point scale) with statements that assessed different acceptability component constructs outlined in the Theoretical Framework of Acceptability (TFA). From March to June 2022, 1500 pharmacy clients and 40 providers were enrolled and completed questionnaires. Most clients liked the intervention (TFA: affective attitude; 96%, 1435/1500) and did not think it would be hard to obtain (TFA: burden; 93%, 1399/1500). All providers agreed the intervention could reduce HPV infection (TFA: perceived effectiveness) and felt confident they could deliver it (TFA: self-efficacy). Among the clients who had received or were planning to receive the HPV vaccine in the future, half (50%, 178/358) preferred a pharmacy-based HPV vaccination. In this study, most Kenyan pharmacy clients and providers perceived a pharmacy-delivered HPV vaccination as highly acceptable; however, more research is needed to test the feasibility and effectiveness of this novel vaccine delivery model in Africa.
全球人乳头瘤病毒(HPV)疫苗接种覆盖率仍然很低,需要采用差异化的疫苗接种模式来扩大接种机会。基于药房的HPV疫苗接种模式可能会吸引到受益女性。我们评估了肯尼亚基苏木县20家私立药房的顾客和工作人员对这种模式的接受度。在问卷调查中,参与者(≥18岁)被要求对评估《可接受性理论框架》(TFA)中概述的不同可接受性组成结构的陈述表示同意程度(5分制)。2022年3月至6月,1500名药房顾客和40名工作人员参与并完成了问卷调查。大多数顾客喜欢这种干预措施(TFA:情感态度;96%,1435/1500),并且认为获取该服务并不困难(TFA:负担;93%,1399/1500)。所有工作人员都同意这种干预措施可以降低HPV感染率(TFA:感知有效性),并对提供该服务充满信心(TFA:自我效能感)。在过去已经接种或未来计划接种HPV疫苗的顾客中,一半(50%,178/358)更倾向于基于药房的HPV疫苗接种。在这项研究中,大多数肯尼亚药房顾客和工作人员认为基于药房的HPV疫苗接种是高度可接受的;然而,需要更多研究来测试这种新型疫苗接种模式在非洲的可行性和有效性。