Maghraby Yasmin R, Labib Rola M, Sobeh Mansour, Farag Mohamed A
Department of Chemistry, The American University in Cairo, New Cairo, Egypt.
Pharmacognosy Department, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.
Food Chem X. 2023 Oct 20;20:100947. doi: 10.1016/j.fochx.2023.100947. eCollection 2023 Dec 30.
Gingerols represent the main bioactive compounds in ginger drugs mostly (F. Zingebraceae) and account for the biological activities and the strong/pungent flavor in ginger. Ginger () rhizome is one of the most valued herbal drugs for ailments' treatment in many ayurvedic medicine asides from its culinary applications as a spice. Gingerols and their dehydrated products shogaols are phenolic phytochemicals found in members of the family and account for most of their effects including anti-inflammatory and anticancer activities. This review entails most of the novel trends related to the extraction, optimization, and formulations of gingerols and shogaols to insure best recoveries and efficacies from their natural resources. Further, it presents a comprehensive overview of the different analytical approaches for the determination of gingerols/shogaols' levels in nutraceuticals to ensure highest quality and for their detection in body fluids for proof of efficacy.
姜辣素是姜科植物（主要是姜）药物中的主要生物活性成分，决定了姜的生物活性以及强烈/辛辣的味道。姜根茎是许多阿育吠陀医学中治疗疾病最受重视的草药之一，此外还作为香料用于烹饪。姜辣素及其脱水产物姜烯酚是姜科植物中的酚类植物化学物质，它们的大部分功效包括抗炎和抗癌活性都归因于此。本综述涵盖了与姜辣素和姜烯酚的提取、优化及制剂相关的大多数新趋势，以确保从其天然来源中获得最佳回收率和功效。此外，还全面概述了用于测定营养保健品中姜辣素/姜烯酚含量以确保最高质量的不同分析方法，以及用于在体液中检测它们以证明功效的方法。
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