Institute of Infectious Diseases, Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, China.
Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Front Cell Infect Microbiol. 2023 Dec 11;13:1290636. doi: 10.3389/fcimb.2023.1290636. eCollection 2023.
Our patient, a 48-year-old man from Guangdong's coastal region, worked selling and processing oysters and other seafood. He started experiencing swelling and pain in his left knee on October 4, 2022, and they got worse over time. The findings of mNGS test showed Vibrio vulnificus infection. The patient had AIDS, hepatitis A and hepatitis B concurrently. He was admitted to the hospital's intensive care unit (ICU) for treatment as his symptoms worsened. We refrained from performing an amputation because the family members expressed a desire to keep the limb. The limb was managed with regular dressing changes, thorough debridement, wound closure, ongoing VSD drainage, and local antibiotic irrigation. The patient's organ function eventually returned to normal, and the systemic infection got better. On November 1, the wound's new granulation tissue had grown well and had gradually crept to cover 80% of the wound. The tissue's blood flow had also improved, indicating a trend of growth and healing.
我们的患者是一位来自广东沿海地区的 48 岁男性，从事销售和加工牡蛎及其他海鲜工作。他于 2022 年 10 月 4 日开始出现左膝肿胀和疼痛，且随着时间的推移逐渐加重。mNGS 检测结果显示创伤弧菌感染。患者同时患有艾滋病、甲型肝炎和乙型肝炎。由于症状加重，他被收入医院重症监护病房（ICU）进行治疗。由于家属希望保留肢体，我们未进行截肢。通过定期更换敷料、彻底清创、伤口闭合、持续负压引流和局部抗生素灌洗来处理该肢体。患者的器官功能最终恢复正常，全身感染情况也得到改善。11 月 1 日，伤口的新肉芽组织生长良好，逐渐覆盖了 80%的伤口。组织的血流也得到改善，显示出生长和愈合的趋势。
