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指南与 LDL 胆固醇管理实践之间存在显著差距:来自韩国心肌梗死学会调查的见解。

Significant Gap Between Guidelines and Practice in the Management of LDL Cholesterol: Insight From the Survey of the Korean Society of Myocardial Infarction.

机构信息

Division of Cardiology, Chung-Ang University Gwangmyeong Hospital, Gwangmyeong, Korea.

Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea.

出版信息

J Korean Med Sci. 2023 Dec 25;38(50):e419. doi: 10.3346/jkms.2023.38.e419.

Abstract

The Guidelines of the 2019 European Society of Cardiology (ESC) and the 5th Society of Lipid and Atherosclerosis (KSoLA) for the Management of Dyslipidemia advocate a more intensive lipid-lowering strategy. However, there is a lack of evidence regarding the current status of lipid management in Korean patients in real-world practice. The Korean Society of Myocardial Infarction conducted a survey among its members of the Korean Society of Cardiology on the new lipid guidelines. Although most participants were aware of the changes in the ESC and the KSoLA guidelines, more than half of them did not agree with lowering the low-density lipoprotein cholesterol levels to < 55 mg/dL, because its safety and efficacy have not yet been proven in Koreans. A substantial disparity exists between lipid management guidelines and current clinical practices, highlighting the necessity for clinical research that specifically targets East Asians and Koreans to bridge this gap.

摘要

2019 年欧洲心脏病学会(ESC)和第 5 届血脂与动脉粥样硬化学会(KSoLA)血脂异常管理指南提倡更积极的降脂策略。然而,在真实世界实践中,关于韩国患者的血脂管理现状,目前还缺乏相关证据。韩国心肌梗死学会对其心脏病学会成员进行了一项关于新血脂指南的调查。尽管大多数参与者了解 ESC 和 KSoLA 指南的变化,但超过一半的人不同意将低密度脂蛋白胆固醇水平降至<55mg/dL,因为其在韩国人群中的安全性和疗效尚未得到证实。血脂管理指南与当前临床实践之间存在显著差异,这突出表明有必要开展专门针对东亚人和韩国人的临床研究,以缩小这一差距。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fe5/10752743/87b0924360eb/jkms-38-e419-g001.jpg

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