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食管闭锁伴气管食管瘘:两例报告。

Esophageal atresia with tracheoesophageal fistula: two case reports.

机构信息

Muhimbili University of Health and Allied Sciences (Muhas), P. O box 65001, Dar es Salaam, Tanzania.

Muhimbili National Hospital (Mnh), Dar es Salaam, Tanzania.

出版信息

J Med Case Rep. 2023 Dec 31;17(1):540. doi: 10.1186/s13256-023-04278-1.

Abstract

BACKGROUND

The incidence of esophageal atresia with tracheoesophageal fistula is 1 out of 3000-5000 live births. Its incidence in lower middle income countries is not known. The infants usually present with excessive secretions or choking while feeding and are at risk for aspiration. The outcome of these infants in lower middle income countries is not encouraging due to delays in referral, sepsis at presentation requiring preoperative stabilization, postoperative complications such as anastomosis leaks, pneumonia, and pneumothorax.

CASE PRESENTATION

We present two African babies who were term infants at age 2 days (male) and 5 days (female) with diagnosis of esophageal atresia and tracheoesophageal fistula. The 5-day-old infant required preoperative stabilization due to sepsis and delayed surgery with a poor postoperative outcome. The 2-day-old infant was preoperatively stable and had a good postoperative outcome. The challenges faced in management of these two cases have been highlighted.

CONCLUSION

Outcome of infants with esophageal atresia and tracheoesophageal fistula in lower middle income countries is not encouraging due to delays in referral and poor postoperative healing attributed to sepsis and recurrent pneumothorax. Timely referral, preoperative condition of the infant, and timely management has shown to be a contributory factor for an improved outcome.

摘要

背景

食管闭锁伴气管食管瘘的发病率为每 3000-5000 例活产儿中有 1 例。中低收入国家的发病率尚不清楚。这些婴儿通常在喂养时出现过多分泌物或窒息,并且有发生吸入的风险。由于转诊延迟、就诊时需要术前稳定的脓毒症、术后吻合口漏、肺炎和气胸等并发症,这些婴儿在中低收入国家的预后并不乐观。

病例介绍

我们介绍了两名非洲婴儿,他们分别是 2 天大(男)和 5 天大(女)的足月婴儿,诊断为食管闭锁伴气管食管瘘。5 天大的婴儿因脓毒症需要术前稳定,手术延迟,术后结果不佳。2 天大的婴儿术前稳定,术后结果良好。强调了管理这两个病例所面临的挑战。

结论

中低收入国家食管闭锁伴气管食管瘘婴儿的预后并不乐观,原因是转诊延迟以及脓毒症和反复气胸导致术后愈合不良。及时转诊、婴儿术前状况以及及时管理已被证明是改善预后的一个因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bc8/10757763/2a0f57bc9b6b/13256_2023_4278_Fig1_HTML.jpg

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