Department of Respiratory Medicine, The Prince Charles Hospital, Brisbane, Queensland, Australia.
Centre of Research Excellence in Pulmonary Fibrosis, Camperdown, New South Wales, Australia.
Respirology. 2024 Feb;29(2):105-135. doi: 10.1111/resp.14656. Epub 2024 Jan 11.
Idiopathic pulmonary fibrosis (IPF) is a progressive disease leading to significant morbidity and mortality. In 2017 the Thoracic Society of Australia and New Zealand (TSANZ) and Lung Foundation Australia (LFA) published a position statement on the treatment of IPF. Since that time, subsidized anti-fibrotic therapy in the form of pirfenidone and nintedanib is now available in both Australia and New Zealand. More recently, evidence has been published in support of nintedanib for non-IPF progressive pulmonary fibrosis (PPF). Additionally, there have been numerous publications relating to the non-pharmacologic management of IPF and PPF. This 2023 update to the position statement for treatment of IPF summarizes developments since 2017 and reaffirms the importance of a multi-faceted approach to the management of IPF and progressive pulmonary fibrosis.
特发性肺纤维化(IPF)是一种进行性疾病,可导致高发病率和死亡率。2017 年,澳大利亚和新西兰胸科学会(TSANZ)和澳大利亚肺脏基金会(LFA)发布了关于 IPF 治疗的立场声明。自那时以来,以吡非尼酮和尼达尼布形式提供的补贴性抗纤维化治疗现已在澳大利亚和新西兰提供。最近,有证据支持尼达尼布用于非特发性进行性肺纤维化(PPF)。此外,还有许多关于 IPF 和 PPF 的非药物治疗管理的出版物。本 IPF 治疗立场声明的 2023 年更新总结了自 2017 年以来的发展,并再次强调了多方面方法管理 IPF 和进行性肺纤维化的重要性。