School of Mathematics and Statistics, The Open University, Milton Keynes, MK7 6AA, UK.
Departments of Statistics, Ecology and Evolution, Molecular Genetics and Cell Biology, University of Chicago, Chicago, 10587, IL, USA.
Sci Rep. 2024 Jan 17;14(1):1468. doi: 10.1038/s41598-024-52028-0.
This manuscript presents an algorithmic approach to cooperation in biological systems, drawing on fundamental ideas from statistical mechanics and probability theory. Fisher's geometric model of adaptation suggests that the evolution of organisms well adapted to multiple constraints comes at a significant complexity cost. By utilizing combinatorial models of fitness, we demonstrate that the probability of adapting to all constraints decreases exponentially with the number of constraints, thereby generalizing Fisher's result. Our main focus is understanding how cooperation can overcome this adaptivity barrier. Through these combinatorial models, we demonstrate that when an organism needs to adapt to a multitude of environmental variables, division of labor emerges as the only viable evolutionary strategy.
这篇手稿提出了一种在生物系统中合作的算法方法,借鉴了统计力学和概率论的基本思想。Fisher 的适应几何模型表明,生物体适应多个约束的进化需要付出巨大的复杂性代价。通过利用适应性的组合模型,我们证明了适应所有约束的概率随约束数量呈指数下降,从而推广了 Fisher 的结果。我们的主要关注点是理解合作如何克服这种适应性障碍。通过这些组合模型,我们证明了当生物体需要适应大量环境变量时,劳动分工是唯一可行的进化策略。