Department of Hematology/Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA.
Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA.
Cancer Med. 2024 Feb;13(3):e6790. doi: 10.1002/cam4.6790. Epub 2024 Jan 17.
This review describes the barriers and challenges faced by older adults of color with cancer and highlights methods to improve their overall care. In the next decade, cancer incidence rates are expected to increase in the United States for people aged ≥65 years. A large proportion will be older adults of color who often have worse outcomes than older White patients. Many issues contribute to racial disparities in older adults, including biological factors and social determinants of health (SDOH) related to healthcare access, socioeconomic concerns, systemic racism, mistrust, and the neighborhood where a person lives. These disparities are exacerbated by age-related challenges often experienced by older adults, such as decreased functional status, impaired cognition, high rates of comorbidities and polypharmacy, poor nutrition, and limited social support. Additionally, underrepresentation of both patients of color and older adults in cancer clinical research results in a lack of adequate data to guide the management of these patients. Use of geriatric assessments (GA) can aid providers in uncovering age-related concerns and personalizing interventions for older patients. Research demonstrates the ability of GA-directed care to result in fewer treatment-related toxicities and improved quality of life, thus supporting the routine incorporation of validated GA into these patients' care. GA can be enhanced by including evaluation of SDOH, which can help healthcare providers understand and address the needs of older adults of color with cancer who face disparities related to their age and race.
这篇综述描述了患有癌症的有色人种老年人所面临的障碍和挑战,并强调了改善他们整体护理的方法。在未来十年,美国≥65 岁人群的癌症发病率预计将会上升。其中很大一部分将是有色人种的老年人,他们的预后往往比老年白人患者差。许多因素导致了老年人中存在种族差异,包括与医疗保健获取相关的生物因素和健康的社会决定因素(SDOH)、社会经济问题、系统性种族主义、不信任以及个人居住的社区。这些差异因老年人经常经历的与年龄相关的挑战而加剧,例如功能状态下降、认知障碍、合并症和多药治疗率高、营养状况差以及社会支持有限。此外,由于癌症临床研究中代表性不足的有色人种患者和老年人,导致缺乏足够的数据来指导这些患者的管理。使用老年评估(GA)可以帮助提供者发现与年龄相关的问题,并为老年患者个性化干预措施。研究表明,GA 指导的护理能够减少与治疗相关的毒性反应,并提高生活质量,从而支持将经过验证的 GA 常规纳入这些患者的护理中。通过评估 SDOH,可以增强 GA,这可以帮助医疗保健提供者了解和满足面临与年龄和种族相关差异的患有癌症的有色人种老年人的需求。