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心血管疾病风险沟通与预防:一项荟萃分析。

Cardiovascular disease risk communication and prevention: a meta-analysis.

机构信息

Institute for Evidence-Based Healthcare, Faculty of Health Sciences and Medicine, Bond University, Robina, QLD, Australia.

School of Health, Medical and Applied Sciences, Central Queensland University, Mackay, QLD, Australia.

出版信息

Eur Heart J. 2024 Mar 27;45(12):998-1013. doi: 10.1093/eurheartj/ehae002.

Abstract

BACKGROUND AND AIMS

Knowledge of quantifiable cardiovascular disease (CVD) risk may improve health outcomes and trigger behavioural change in patients or clinicians. This review aimed to investigate the impact of CVD risk communication on patient-perceived CVD risk and changes in CVD risk factors.

METHODS

PubMed, Embase, and PsycINFO databases were searched from inception to 6 June 2023, supplemented by citation analysis. Randomized trials that compared any CVD risk communication strategy versus usual care were included. Paired reviewers independently screened the identified records and extracted the data; disagreements were resolved by a third author. The primary outcome was the accuracy of risk perception. Secondary outcomes were clinician-reported changes in CVD risk, psychological responses, intention to modify lifestyle, and self-reported changes in risk factors and clinician prescribing of preventive medicines.

RESULTS

Sixty-two trials were included. Accuracy of risk perception was higher among intervention participants (odds ratio = 2.31, 95% confidence interval = 1.63 to 3.27). A statistically significant improvement in overall CVD risk scores was found at 6-12 months (mean difference = -0.27, 95% confidence interval = -0.45 to -0.09). For primary prevention, risk communication significantly increased self-reported dietary modification (odds ratio = 1.50, 95% confidence interval = 1.21 to 1.86) with no increase in intention or actual changes in smoking cessation or physical activity. A significant impact on patients' intention to start preventive medication was found for primary and secondary prevention, with changes at follow-up for the primary prevention group.

CONCLUSIONS

In this systematic review and meta-analysis, communicating CVD risk information, regardless of the method, reduced the overall risk factors and enhanced patients' self-perceived risk. Communication of CVD risk to patients should be considered in routine consultations.

摘要

背景与目的

了解可量化的心血管疾病(CVD)风险可能会改善患者或临床医生的健康结果并引发行为改变。本综述旨在调查 CVD 风险沟通对患者感知的 CVD 风险以及 CVD 风险因素变化的影响。

方法

从建库到 2023 年 6 月 6 日,我们在 PubMed、Embase 和 PsycINFO 数据库中进行了检索,并辅以引文分析。纳入了比较任何 CVD 风险沟通策略与常规护理的随机试验。由两名评审员独立筛选所确定的记录并提取数据;意见分歧由第三名评审员解决。主要结局是风险感知的准确性。次要结局是临床医生报告的 CVD 风险变化、心理反应、改变生活方式的意愿以及自我报告的风险因素变化和临床医生开具预防药物的情况。

结果

纳入了 62 项试验。干预组参与者的风险感知准确性更高(比值比=2.31,95%置信区间=1.63 至 3.27)。在 6-12 个月时发现总体 CVD 风险评分有统计学显著改善(平均差异=-0.27,95%置信区间=-0.45 至-0.09)。对于一级预防,风险沟通显著增加了自我报告的饮食改变(比值比=1.50,95%置信区间=1.21 至 1.86),但并未增加戒烟或增加体力活动的意愿或实际改变。对于一级和二级预防,发现风险沟通对患者开始预防用药的意愿有显著影响,一级预防组在随访时发生了变化。

结论

在本系统评价和荟萃分析中,无论方法如何,沟通 CVD 风险信息都降低了总体风险因素并增强了患者的自我感知风险。在常规咨询中应考虑向患者传达 CVD 风险信息。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd81/10972690/9d32da567960/ehae002_ga.jpg

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