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睡眠-觉醒状态差异并不损害失眠认知行为疗法的疗效:来自大型临床样本的研究结果。

Sleep-wake state discrepancy does not impair the efficacy of cognitive behavioural therapy for insomnia: Findings from a large clinic sample.

作者信息

Moulder Zoe, Sweetman Alexander, Lovato Nicole, Micic Gorica, Lack Leon, Scott Hannah

机构信息

Flinders Health and Medical Research Institute: Sleep Health, College of Medicine and Public Health, Flinders University, Bedford Park, South Australia, Australia.

出版信息

J Sleep Res. 2024 Oct;33(5):e14142. doi: 10.1111/jsr.14142. Epub 2024 Jan 21.

Abstract

The current study determined the extent to which sleep-wake state discrepancy impairs the efficacy of cognitive behavioural therapy for insomnia in a real-world clinical sample. Sleep-wake state discrepancy occurs when there is an inconsistency between a person's subjective and objective sleep, and is a common phenomenon amongst patients with insomnia. Limited information is available on the effectiveness of cognitive behavioural therapy for insomnia in treating patients who experience significant sleep-wake state discrepancy in "real-world" samples. In the present study, all patients with insomnia received cognitive behavioural therapy for insomnia through an outpatient insomnia program (N = 386; mean age = 51.96 years, SD = 15.62; 65.97% [N = 254] female). Prior to treatment, participants completed a polysomnography sleep study and sleep diary, which was used to calculate sleep-wake state discrepancy. At pre-treatment, post-treatment and 3-month follow-up, participants completed the Insomnia Severity Index and other questionnaires, and 1 week of sleep diaries from which sleep-onset latency, wake after sleep onset and other sleep variables were calculated. There were no differences in self-reported sleep-onset latency, wake after sleep onset or Insomnia Severity Index scores at post-treatment or 3-month follow-up between quintiles of sleep-wake state discrepancy. These results indicate that sleep-wake state discrepancy at pre-treatment does not predict treatment response to cognitive behavioural therapy for insomnia. Future research could examine multi-night assessments of sleep-wake state discrepancy to determine whether variations in discrepancy may relate to pre-treatment insomnia severity and cognitive behavioural therapy for insomnia outcomes.

摘要

本研究确定了在一个真实世界的临床样本中,睡眠-觉醒状态差异对失眠认知行为疗法疗效的损害程度。当一个人的主观睡眠和客观睡眠不一致时,就会出现睡眠-觉醒状态差异,这在失眠患者中是一种常见现象。关于失眠认知行为疗法在治疗“真实世界”样本中存在显著睡眠-觉醒状态差异的患者时的有效性,现有信息有限。在本研究中,所有失眠患者都通过门诊失眠项目接受了失眠认知行为疗法(N = 386;平均年龄 = 51.96岁,标准差 = 15.62;65.97%[N = 254]为女性)。在治疗前,参与者完成了一项多导睡眠图睡眠研究和睡眠日记,用于计算睡眠-觉醒状态差异。在治疗前、治疗后和3个月随访时,参与者完成了失眠严重程度指数和其他问卷,以及1周的睡眠日记,从中计算出入睡潜伏期、睡眠中觉醒时间和其他睡眠变量。在睡眠-觉醒状态差异的五分位数之间,治疗后或3个月随访时,自我报告的入睡潜伏期、睡眠中觉醒时间或失眠严重程度指数得分没有差异。这些结果表明,治疗前的睡眠-觉醒状态差异不能预测对失眠认知行为疗法的治疗反应。未来的研究可以检查对睡眠-觉醒状态差异的多晚评估,以确定差异的变化是否可能与治疗前的失眠严重程度和失眠认知行为疗法的结果有关。

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