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用于卓越医疗保健的3D打印概念与发展

Concept and Evolution in 3D Printing for Excellence in Healthcare.

作者信息

Sinha Priyank, Lahare Preeti, Sahu Meena, Cimler Richard, Schnitzer Marek, Hlubenova Jana, Hudak Radovan, Singh Namrata, Gupta Bhanushree, Kuca Kamil

机构信息

Department of Chemistry, Centre for Basic Sciences, Pandit Ravishankar Shukla University, Raipur 492010, Chhattisgarh, India.

Department of Chemistry, Faculty of Science, Center for Applied Technologies, University of Hradec Kralove, Rokitanskeho 62, Hradec Kralove, Czech Republic.

出版信息

Curr Med Chem. 2025;32(5):831-879. doi: 10.2174/0109298673262300231129102520.

Abstract

Three-dimensional printing (3DP) has gained popularity among scientists and researchers in every field due to its potential to drastically reduce energy costs for the production of customized products by utilizing less energy-intensive machines as well as minimizing material waste. The 3D printing technology is an additive manufacturing approach that uses material layer-by-layer fabrication to produce the digitally specified 3D model. The use of 3D printing technology in the pharmaceutical sector has the potential to revolutionize research and development by providing a quick and easy means to manufacture personalized one-off batches, each with unique dosages, distinct substances, shapes, and sizes, as well as variable release rates. This overview addresses the concept of 3D printing, its evolution, and its operation, as well as the most popular types of 3D printing processes utilized in the health care industry. It also discusses the application of these cutting-edge technologies to the pharmaceutical industry, advancements in various medical fields and medical equipment, 3D bioprinting, the most recent initiatives to combat COVID-19, regulatory frameworks, and the major challenges that this technology currently faces. In addition, we attempt to provide some futuristic approaches to 3DP applications.

摘要

三维打印(3DP)在各个领域的科学家和研究人员中越来越受欢迎,因为它有可能通过使用能源消耗较低的机器并尽量减少材料浪费,大幅降低定制产品生产的能源成本。3D打印技术是一种增材制造方法,它通过逐层制造材料来生产数字指定的3D模型。在制药领域使用3D打印技术有可能彻底改变研发方式,提供一种快速简便的方法来制造个性化的一次性批次产品,每个批次都有独特的剂量、不同的物质、形状和尺寸,以及可变的释放速率。本综述阐述了3D打印的概念、发展历程及其操作方式,以及医疗保健行业中最常用的3D打印工艺类型。还讨论了这些前沿技术在制药行业的应用、各个医学领域和医疗设备的进展、3D生物打印、抗击COVID-19的最新举措、监管框架以及该技术目前面临的主要挑战。此外,我们尝试提供一些3DP应用的未来发展方向。

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