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创伤后应激障碍患病率与分娩:DSM-5 引入和 COVID-19 大流行后的更新荟萃分析。

Posttraumatic stress disorder prevalence and childbirth: update meta-analysis after the introduction of the DSM-5 and COVID-19 pandemic.

机构信息

Medical School of Ribeirão Preto. São Paulo University, Avenida Dos Bandeirantes, 3900, Ribeirão Preto, SP, 14048-900, Brazil.

National Institute of Science and Technology (INCT-TM, CNPq), Brasília, Brazil.

出版信息

Arch Womens Ment Health. 2024 Jun;27(3):337-357. doi: 10.1007/s00737-024-01423-7. Epub 2024 Jan 24.

Abstract

PURPOSE

Meta-analyses were previously performed to estimate PTSD prevalence in the postpartum period. Significant events that could impact this outcome occurred in the last decade, such as the publication of the DSM-5 in 2013 and the COVID-19 pandemic in 2020. This systematic literature review with a meta-analysis addressed studies published after 2014 to estimate PTSD prevalence after childbirth.

METHOD

The methodological guidelines recommended by PRISMA were followed. The meta-analysis estimate was the proportion of PTSD cases. The restricted maximum likelihood (REML) was the method adopted for estimation in addition to multilevel random effect models. Subgroup analyses were performed to assess the impact of interest variables.

RESULTS

The estimated prevalence was 0.10 (95%CI: 0.8-0.13; I = 98.5%). No significant differences were found regarding the introduction of the DSM-5 (p = 0.73) or COVID-19 (p = 0.97), but instead, between low- and middle-income countries, e.g., the Middle East presents a higher prevalence (p < 0.01) than European countries.

CONCLUSIONS

There is a potential increase in PTSD prevalence rates after childbirth in the last decade not associated with the pandemic or the current diagnostic classification. Most studies showed a methodological fragility that must be overcome to understand this phenomenon better and support preventive actions and treatment for puerperal women.

摘要

目的

先前进行了荟萃分析,以估计产后期间创伤后应激障碍(PTSD)的患病率。在过去十年中,发生了一些可能影响这一结果的重大事件,例如 2013 年发布的 DSM-5 和 2020 年的 COVID-19 大流行。本系统文献回顾和荟萃分析旨在评估 2014 年后发表的研究,以估计产后 PTSD 的患病率。

方法

遵循 PRISMA 推荐的方法学指南。荟萃分析估计值是 PTSD 病例的比例。除了多级随机效应模型外,还采用受限最大似然(REML)方法进行估计。进行了亚组分析,以评估感兴趣变量的影响。

结果

估计的患病率为 0.10(95%CI:0.8-0.13;I=98.5%)。关于 DSM-5 的引入(p=0.73)或 COVID-19(p=0.97),没有发现显著差异,但在中低收入国家之间,例如中东,其患病率较高(p<0.01),而欧洲国家则较低。

结论

在过去十年中,产后 PTSD 患病率可能有所增加,与大流行或当前的诊断分类无关。大多数研究显示出方法学脆弱性,必须克服这些脆弱性,以更好地理解这一现象,并为产后妇女提供预防措施和治疗。

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