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[疼痛与颈部肌张力障碍]

[Pain and cervical dystonia].

作者信息

Hamami Feline, Bäumer Tobias

机构信息

Institut für Systemische Motorikforschung, Center of Brain, Behavior and Metabolism (CBBM), Universität zu Lübeck, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, 23562, Lübeck, Deutschland.

出版信息

Schmerz. 2024 Feb;38(1):41-47. doi: 10.1007/s00482-024-00790-5. Epub 2024 Jan 24.

Abstract

BACKGROUND

Dystonia is a hyperkinetic movement disorder that results in twisting, cramps and tremors due to sustained or intermittent muscle contractions. Cervical dystonia is the most common form of dystonia, in which the head, neck and/or shoulder areas are affected. In addition to these motor symptoms, pain and psychiatric symptoms are frequent in (cervical) dystonia.

OBJECTIVE

Description of the incidence and evaluation of pain in cervical dystonia, summary and discussion of treatment options and effects.

MATERIAL AND METHODS

In this review article the results in the scientific literature on pain in dystonia are summarized and discussed.

RESULTS

Compared to other forms of dystonia, pain occurs most frequently in patients with cervical dystonia. A large proportion of patients with cervical dystonia suffer from pain, which contributes most to impairment of the patient. The motor symptoms of dystonia are usually treated with botulinum toxin injections. These have a muscle relaxing effect and also relieve pain. The study situation on the occurrence and treatment of pain in other forms of dystonia is so far very limited. Pain can dominate the clinical picture in patients with cervical dystonia. Evaluation of pain in cervical dystonia can be performed using standardized questionnaires.

CONCLUSION

It is important to ask patients with cervical dystonia about pain and to consider it in treatment planning and evaluation. Vice versa, if pain is present the possibility of a causative dystonia should also be considered. For pain assessment there are some newly developed questionnaires to assess pain in a standardized way in patients with dystonia. Further research is needed to better understand the pathomechanisms of pain in dystonia.

摘要

背景

肌张力障碍是一种运动亢进性运动障碍,由于肌肉持续或间歇性收缩导致扭曲、痉挛和震颤。颈部肌张力障碍是肌张力障碍最常见的形式,其中头部、颈部和/或肩部区域受到影响。除了这些运动症状外,(颈部)肌张力障碍患者还经常出现疼痛和精神症状。

目的

描述颈部肌张力障碍的发病率及疼痛评估,总结并讨论治疗选择及效果。

材料与方法

在这篇综述文章中,总结并讨论了科学文献中关于肌张力障碍疼痛的研究结果。

结果

与其他形式的肌张力障碍相比,疼痛在颈部肌张力障碍患者中最为常见。很大一部分颈部肌张力障碍患者遭受疼痛折磨,这对患者的功能损害最大。肌张力障碍的运动症状通常用肉毒杆菌毒素注射治疗。这些药物具有肌肉松弛作用,也能缓解疼痛。目前关于其他形式肌张力障碍疼痛的发生和治疗的研究情况非常有限。疼痛在颈部肌张力障碍患者的临床表现中可能占主导地位。颈部肌张力障碍的疼痛评估可以使用标准化问卷进行。

结论

询问颈部肌张力障碍患者是否疼痛并在治疗计划和评估中予以考虑很重要。反之,如果存在疼痛,也应考虑肌张力障碍作为病因的可能性。对于疼痛评估,有一些新开发的问卷可用于以标准化方式评估肌张力障碍患者的疼痛。需要进一步研究以更好地理解肌张力障碍疼痛的发病机制。

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