Oster Brittany, Hameed Daniel, Dubin Jeremy A, Bains Sandeep S, Shul Craig, Mont Michael, Delanois Ronald E
University of Maryland, Orthopedic Surgery Department, Baltimore, MD, USA.
LifeBridge Health, Sinai Hospital of Baltimore, Rubin Institute for Advanced Orthopedics, Baltimore, MD, USA.
J Orthop. 2023 Dec 21;50:149-154. doi: 10.1016/j.jor.2023.12.008. eCollection 2024 Apr.
Obstructive sleep apnea (OSA) impacts approximately 936 million individuals globally and is known to complicate post-surgical recovery, particularly after total hip arthroplasty (THA). While continuous positive airway pressure (CPAP) is commonly recommended for managing OSA, its effect on THA recovery remains uncertain. The study aimed to assess the impact of CPAP use on post-THA outcomes in patients with OSA, focusing on medical complications and periprosthetic joint infection (PJI) at 90 days and 1 year.
A national, all-payer database was utilized to identify patients undergoing primary THA between 2010 and 2021. Patients with OSA were stratified based on CPAP use through propensity score matching. Three matched groups were formed: OSA without CPAP, OSA with CPAP, and no OSA. Medical and surgical complications were assessed at 90 days and 1 year post-THA.
Patients with OSA using CPAP exhibited more baseline comorbidities than those without CPAP. CPAP use was associated with inferior outcomes, including higher odds of PJI, wound complications, and venous thromboembolism at 90 days and 1 year post-THA. These trends were consistent even after adjusting for confounders.
CPAP use, indicative of severe OSA, was linked to worse post-THA outcomes, emphasizing the importance of recognizing OSA severity preoperatively. The study does not advocate for or against CPAP use but underscores the heightened risk in this patient population, guiding clinicians in tailoring perioperative strategies and counseling patients about potential risks.
阻塞性睡眠呼吸暂停(OSA)在全球约影响9.36亿人,已知会使术后恢复复杂化,尤其是在全髋关节置换术(THA)后。虽然持续气道正压通气(CPAP)通常被推荐用于管理OSA,但其对THA恢复的影响仍不确定。该研究旨在评估CPAP使用对OSA患者THA术后结局的影响,重点关注90天和1年时的医疗并发症和假体周围关节感染(PJI)。
利用一个全国性的全付费者数据库来识别2010年至2021年间接受初次THA的患者。通过倾向得分匹配,根据CPAP使用情况对OSA患者进行分层。形成了三个匹配组:未使用CPAP的OSA组、使用CPAP的OSA组和无OSA组。在THA术后90天和1年评估医疗和手术并发症。
使用CPAP的OSA患者比未使用CPAP的患者表现出更多的基线合并症。使用CPAP与较差的结局相关,包括在THA术后90天和1年时PJI、伤口并发症和静脉血栓栓塞的几率更高。即使在调整混杂因素后,这些趋势仍然一致。
使用CPAP表明存在严重OSA,与THA术后更差的结局相关,强调术前识别OSA严重程度的重要性。该研究不主张支持或反对使用CPAP,但强调了该患者群体中更高的风险,指导临床医生制定围手术期策略并向患者咨询潜在风险。