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在 COVID-19 大流行期间患有糖尿病或高血压的成年人的体重趋势:一项使用 OpenSAFELY 的观察性研究。

Weight trends among adults with diabetes or hypertension during the COVID-19 pandemic: an observational study using OpenSAFELY.

机构信息

Wolfson Institute of Population Health, Queen Mary University of London, London.

Bennett Institute for Applied Data Science, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford.

出版信息

Br J Gen Pract. 2024 Oct 31;74(748):e767-e776. doi: 10.3399/BJGP.2023.0492. Print 2024 Nov.

DOI:10.3399/BJGP.2023.0492
PMID:38296356
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11466294/
Abstract

BACKGROUND

COVID-19 pandemic restrictions may have influenced behaviours related to weight.

AIM

To describe patterns of weight change among adults living in England with type 2 diabetes (T2D) and/or hypertension during the pandemic.

DESIGN AND SETTING

An observational cohort study using the routinely collected health data of approximately 40% of adults living in England, accessed through the OpenSAFELY service inside TPP.

METHOD

Clinical and sociodemographic characteristics associated with rapid weight gain (>0.5 kg/m/year) were investigated using multivariable logistic regression.

RESULTS

Data were extracted on adults with T2D ( = 1 231 455, 43.9% female, and 76.0% White British) or hypertension ( = 3 558 405, 49.7% female, and 84.3% White British). Adults with T2D lost weight overall (median δ = -0.1 kg/m/year [interquartile range {IQR} -0.7-0.4]). However, rapid weight gain was common (20.7%) and associated with the following: sex (male versus female: adjusted odds ratio [aOR] 0.78 [95% confidence interval {CI} = 0.77 to 0.79]); age (older age reduced odds, for example, aged 60-69 years versus 18-29 years: aOR 0.66 [95% CI = 0.61 to 0.71]); deprivation (least deprived Index of Multiple Deprivation [IMD] quintile versus most deprived IMD quintile: aOR 0.87 [95% CI = 0.85 to 0.89]); White ethnicity (Black versus White: aOR 0.95 [95% CI = 0.92 to 0.98]); mental health conditions (for example, depression: aOR 1.13 [95% CI = 1.12 to 1.15]); and diabetes treatment (non-insulin treatment versus no pharmacological treatment: aOR 0.68 [95% CI = 0.67 to 0.69]). Adults with hypertension maintained stable weight overall (median δ = 0.0 kg/m/year [IQR -0.6-0.5]); however, rapid weight gain was common (24.7%) and associated with similar characteristics as in T2D.

CONCLUSION

Among adults living in England with T2D and/or hypertension, rapid pandemic weight gain was more common among females, younger adults, those living in more deprived areas, and those with mental health conditions.

摘要

背景

COVID-19 大流行期间的限制可能会影响与体重相关的行为。

目的

描述在大流行期间,英国患有 2 型糖尿病(T2D)和/或高血压的成年人的体重变化模式。

设计和设置

这是一项使用常规收集的大约 40%英国成年人健康数据的观察性队列研究,通过 TPP 内部的 OpenSAFELY 服务获得。

方法

使用多变量逻辑回归调查与体重快速增加(>0.5kg/m/年)相关的临床和社会人口统计学特征。

结果

共提取了患有 T2D(n=1231455,43.9%为女性,76.0%为白种英国人)或高血压(n=3558405,49.7%为女性,84.3%为白种英国人)的成年人的数据。患有 T2D 的成年人总体上体重减轻(中位数 δ=-0.1kg/m/年[四分位距{IQR}=-0.7-0.4])。然而,体重快速增加很常见(20.7%),与以下因素有关:性别(男性与女性:调整后的优势比[aOR]0.78[95%置信区间{CI}=0.77 至 0.79]);年龄(年龄较大的人降低了几率,例如,60-69 岁与 18-29 岁相比:aOR 0.66[95%CI=0.61 至 0.71]);贫困程度(最不贫困的多重剥夺指数[ IMD]五分位数与最贫困的 IMD 五分位数相比:aOR 0.87[95%CI=0.85 至 0.89]);白种人种族(黑人与白人相比:aOR 0.95[95%CI=0.92 至 0.98]);心理健康状况(例如,抑郁症:aOR 1.13[95%CI=1.12 至 1.15]);以及糖尿病治疗(非胰岛素治疗与无药物治疗相比:aOR 0.68[95%CI=0.67 至 0.69])。患有高血压的成年人总体上体重保持稳定(中位数 δ=0.0kg/m/年[IQR=-0.6-0.5]);然而,体重快速增加很常见(24.7%),与 T2D 中的相似特征有关。

结论

在英国患有 T2D 和/或高血压的成年人中,女性、年轻成年人、生活在贫困地区的成年人和患有心理健康状况的成年人更常见体重快速增加。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8753/11526761/e8114f458a84/bjgpnov-2024-74-748-e767-5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8753/11526761/5d429758bc86/bjgpnov-2024-74-748-e767-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8753/11526761/9859a0e961c9/bjgpnov-2024-74-748-e767-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8753/11526761/0f8661fe4ba8/bjgpnov-2024-74-748-e767-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8753/11526761/97e0c00e1e33/bjgpnov-2024-74-748-e767-4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8753/11526761/e8114f458a84/bjgpnov-2024-74-748-e767-5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8753/11526761/5d429758bc86/bjgpnov-2024-74-748-e767-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8753/11526761/9859a0e961c9/bjgpnov-2024-74-748-e767-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8753/11526761/0f8661fe4ba8/bjgpnov-2024-74-748-e767-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8753/11526761/97e0c00e1e33/bjgpnov-2024-74-748-e767-4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8753/11526761/e8114f458a84/bjgpnov-2024-74-748-e767-5.jpg

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