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作为多级手术一部分的髌骨下移能否改善脑瘫蹲伏步态患儿的膝关节运动学?一项比较研究的荟萃分析。

Does patella lowering as part of multilevel surgery improve knee kinematics in children with cerebral palsy and crouch gait? A meta-analysis of comparative studies.

作者信息

Galán-Olleros María, Lerma-Lara Sergio, Torres-Izquierdo Beltran, Ramírez-Barragán Ana, Egea-Gámez Rosa M, Hosseinzadeh Pooya, Martínez-Caballero Ignacio

机构信息

Neuro-Orthopaedic Unit, Orthopaedic Surgery and Traumatology Department, Hospital Infantil Universitario Niño Jesús, Madrid, Spain.

Departament of Physiotherapy, Centro Superior de Estudios Universitarios La Salle, Universidad Autónoma de Madrid, Madrid, Spain.

出版信息

J Child Orthop. 2023 Dec 14;18(1):13-25. doi: 10.1177/18632521231217542. eCollection 2024 Feb.

Abstract

PURPOSE

To evaluate differences in knee kinematic outcomes of patellar-lowering surgery, specifically patellar tendon advancement or patellar tendon shortening, compared with no-patellar-lowering surgery in multilevel surgery for children with cerebral palsy and crouch gait.

METHODS

Four databases were searched to retrieve studies published from inception until 2023. Three reviewers independently screened for studies with observational or randomized control designs, comparing two groups of patients with cerebral palsy and crouch gait who underwent multilevel surgery (with patellar-lowering surgery versus no-patellar-lowering surgery), where various gait analysis outcomes were reported (CRD42023450692). The risk of bias was assessed with the Risk Of Bias In Non-randomised Studies - of Interventions (ROBINS-I) tool.

RESULTS

Seven studies (249 patients and 368 limbs) met the eligibility criteria. Patients undergoing patellar-lowering surgery demonstrated statistically significant improvements in knee flexion at initial contact (mean difference = -6.39; 95% confidence interval = [-10.4, -2.75];  = 0.0006;  = 84%), minimum knee flexion in stance (mean difference = -14.27; 95% confidence interval = [-18.31, -10.23];  < 0.00001;  = 89%), and clinical knee flexion contracture (mean difference = -5.6; 95% confidence interval = [-9.59, -1.6];  = 0.006;  = 95%), with a significant increase in anterior pelvic tilt (mean difference = 2.97; 95% confidence interval = [0.58, 5.36];  = 0.01;  = 15%). However, improvements in gait deviation index and decrease in peak knee flexion in swing did not reach statistical significance. Subgroup analysis reduced heterogeneity and revealed (1) greater improvement using patellar tendon shortening versus patellar tendon advancement techniques; (2) lack of knee flexion contracture improvement in high-quality or longer-term studies; (3) longer-term improvement only in minimum knee flexion in stance, with a decrease in peak knee flexion in swing; and (4) an inability to assess the potential benefit of rectus femoris procedure and hamstring preservation.

CONCLUSIONS

Overall, the combination of patellar-lowering surgery with multilevel surgery demonstrated superior improvements in stance-phase knee kinematics compared with multilevel surgery alone, despite an increase in anterior pelvic tilt and a longer-term knee flexion reduction during the swing phase.

LEVEL OF EVIDENCE

Level III, Systematic review of level III studies.

摘要

目的

评估在脑瘫和蹲伏步态儿童的多级手术中,与不进行髌骨降低手术相比,髌骨降低手术(具体为髌腱前移或髌腱缩短)在膝关节运动学结果方面的差异。

方法

检索了四个数据库,以获取从数据库建立至2023年发表的研究。三名评审员独立筛选具有观察性或随机对照设计的研究,比较两组接受多级手术(进行髌骨降低手术与不进行髌骨降低手术)的脑瘫和蹲伏步态患者,这些研究报告了各种步态分析结果(CRD42023450692)。使用非随机干预性研究的偏倚风险(ROBINS-I)工具评估偏倚风险。

结果

七项研究(249例患者和368条肢体)符合纳入标准。接受髌骨降低手术的患者在初始接触时膝关节屈曲有统计学显著改善(平均差异=-6.39;95%置信区间=[-10.4, -2.75];P=0.0006;I²=84%),站立位最小膝关节屈曲有改善(平均差异=-14.27;95%置信区间=[-18.31, -10.23];P<0.00001;I²=89%),以及临床膝关节屈曲挛缩有改善(平均差异=-5.6;95%置信区间=[-9.59, -1.6];P=0.006;I²=95%),同时骨盆前倾显著增加(平均差异=2.97;95%置信区间=[0.58, 5.36];P=0.01;I²=15%)。然而,步态偏差指数的改善和摆动期膝关节最大屈曲度的降低未达到统计学显著性。亚组分析减少了异质性,并显示:(1)与髌腱前移技术相比,使用髌腱缩短技术有更大改善;(2)在高质量或长期研究中膝关节屈曲挛缩无改善;(3)仅在站立位最小膝关节屈曲方面有长期改善,摆动期膝关节最大屈曲度降低;(4)无法评估股直肌手术和保留腘绳肌的潜在益处。

结论

总体而言,与单独进行多级手术相比,髌骨降低手术与多级手术相结合在站立期膝关节运动学方面显示出更优的改善,尽管骨盆前倾增加,且摆动期膝关节屈曲度有长期降低。

证据级别

三级,对三级研究的系统评价。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a47/10859119/c6a06cdbbde1/10.1177_18632521231217542-fig1.jpg

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